59786 Results for: "Rurki+do+dializy&pageNo=50&view=list"

Supplier: Merck

Phosphatase substrate has been used as a substrate in tartrate-resistant acid phosphatase (TRAP) assay and alkaline phosphatase (ALP). Substrate for the determination of acid and alkaline phosphatases.

Supplier: KGW

COLD TRAP TYP KF 54V-K16-Z-360 1 * 1 items

Supplier: Mettler - Toledo

Not only do these meters measure pH and ORP with classical sensors, but they also support pH measurement with ISFET technology. The instruments can effectively cope with complex applications and stringent requirements in regulated markets as well as with routine measurement tasks in laboratories.

Supplier: LAUDA

The Alpha heating thermostats have an easy to use control console featuring three button operation and large, clear LED display, ensuring easy navigation through the menu. The thermostats are suitable for use with non flammable liquids (water, water/glycol mixtures). Units can provide both internal and external thermostating. Temperature stability of ±0,05 K gives precise heating and cooling suitable for a wide range of applications. Using an optional pump circulation set and a cooling coil, the heating thermostat can be expanded to create a fully fledged thermostating system.

Supplier: MP Biomedicals

p nitrophenol is the substrate of choice for use with alkaline phosphatase in ELISA procedures. This substrate produces a soluble end product that is yellow in color and can be read spectrophotometrically at 405 nm. The pNPP reaction may be stopped with 3 M NaOH and read at 405 nm.

Supplier: Portwest

This garment was voted number one in its class by customers when tested against leading competitors. The breathable and waterproof qualities of the jacket ensure that you are kept 100% dry and comfortable at all times.

Supplier: MACHEREY-NAGEL

The NANOCOLOR® Advance combines the advantages of a portable compact photometer with the high-precision measurement technology and reliability of a benchtop spectrophotometer.

Supplier: Thermo Scientific

Uv-c irradiator spot k 115 v 60 hz 1 * 1 items

Supplier: Greiner Bio-One

FOAM PLUG 50MM CEAPRENE 1 * 315 items

Supplier: Epredia

Microslide Superfrost 90° CC white glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide Superfrost Print 90° yellow glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide superfrost 90° cc pink glass+box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide Superfrost 45° blue glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Merck

Phosphatase substrate has been used as a substrate in tartrate-resistant acid phosphatase (TRAP) assay and alkaline phosphatase (ALP). Substrate for the determination of acid and alkaline phosphatases.

Supplier: VELP SCIENTIFIC

The procedure for determining dietary fibre exposes the sample to a series of enzymatic digestions that simulate the real digestive process which takes place in the human or animal digestive tract, calculating the undigested residue remaining at the end of the analysis. Generally dietary fibre analysis is carried out on foods intended for human consumption whereas raw fibre analysis is carried out on animal feeds or on raw materials of vegetable origin, eg. cereals. The GDE performs enzymatic digestion, a delicate phase where samples are immersed in a thermostatic water bath and stirred. Continuous and constant sample mixing is necessary in order to prevent the sample from overheating. The unit consists of an immersion thermostat, a transparent polycarbonate tank and a VELP 6-place magnetic stirrer to ensure excellent thermoregulation and precision. The use of deionised water is recommended as it eliminates any possible cause of limescale.

Supplier: SAMCO

PIPETTE T/FER EXT/F/TIP STER PE 1.7ML 1 * 3.200 items

Supplier: Amarell

General purpose thermometer, enclosed scale, cap. lens front, red special liquid, -10+60:1C, total immersion, 200x7-8mm long, with ring at top 1 * 1 items

Supplier: Epredia

Microslide Superfrost 45° yellow glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: JM BROSSERIE

BRUSH CLEAN Ø50MM L=200MM PA WH 0.6MM 1 * 10 items

Supplier: Epredia

Microslide Superfrost 90° CC yellow glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide Superfrost 90° CC blue glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide Superfrost 45° green glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide 45° frosted 20mm glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: P D UMWELTSCHUTZ UND PRUEFGERA

Federklammer für Erlenmeyerkolben 500 ml 1 * 1 ST

Supplier: ProSci Inc.

tumour Necrosis Factor- alpha (TNF- alpha) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF- alpha while cells that express CD8 secrete little or no TNF- alpha. Synthesis of TNF- alpha can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumour activity of TNF- alpha has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF- alpha mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF- alpha that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumour activity and reduced systemic toxicity in mice compared with murine TNF- alpha, which binds to both murine TNF receptors. Based on these results, many TNF- alpha mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumour cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF- alpha High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.

Supplier: ProSci Inc.

R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/β-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for β-catenin stabilisation. A putative nuclear localisation signal at the C-terminus may allow some expression in the nucleus. Potential isoforms of 200 and 236 aa have an alternate, shorter N-terminus or are missing aa 146-208, respectively. R-Spondin-1 is expressed in early development at the roof plate boundary and is thought to contribute to dorsal neural tube development. Human RSPO1 disruption results in a recessive syndrome characterized by XX sex reversal, palmoplantar hyperkeratosis and predisposition to squamous cell carcinoma of the skin. It has been shown that the complete female-to-male sex reversal is due to the absence of the testis-determining gene, SRY. R-Spondin-1 regulates Wnt/β-catenin by competing with the Wnt antagonist DKK1 for binding to the Wnt co receptors, Kremen and LRP6, reducing their DKK1 mediated internalisation. Reports differ on whether R-spondin 1 binds LRP6 directly.

Supplier: VICI

C75TH-1673EUHB - 3 mpos trapping-path, u-electric, USB 1/16*.25mm, 50C/10000psi liq, N60C/E3 Electric Universal Actuator Serial interface: USB 1 * 1 items

Supplier: LP ITALIANA

BOTTLE HDPE SQUARE 50ML WITH GASKET 24MM 1 * 180 items

Supplier: ProSci Inc.

The Fas is also known as FAS receptor (FasR), apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6). is a death receptor on the surface of cells that leads to programmed cell death (apoptosis). It is one of two apoptosis pathways, the other being the mitochondrial pathway. FasR is located on chromosome 10 in humans and 19 in mice. Similar sequences related by evolution (orthologs) are found in most mammals. Fas forms the death-inducing signaling complex (DISC) upon ligand binding. Membrane-anchored Fas ligand trimer on the surface of an adjacent cell causes trimerization of Fas receptor. This event is also mimicked by binding of an agonistic Fas antibody, though some evidence suggests that the apoptotic signal induced by the antibody is unreliable in the study of Fas signaling. To this end, several clever ways of trimerizing the antibody for in vitro research have been employed.Upon ensuing death domain (DD) aggregation, the receptor complex is internalized via the cellular endosomal machinery. This allows the adaptor molecule FADD to bind the death domain of Fas through its own death domain. Recently, Fas has also been shown to promote tumor growth, since during tumor progression, it is frequently downregulated or cells are rendered apoptosis resistant. Cancer cells in general, regardless of their Fas apoptosis sensitivity, depend on constitutive activity of Fas. This is stimulated by cancer-produced Fas ligand for optimal growth.

Supplier: ProSci Inc.

tumour Necrosis Factor- alpha (TNF- alpha) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF- alpha while cells that express CD8 secrete little or no TNF- alpha. Synthesis of TNF- alpha can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumour activity of TNF- alpha has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF- alpha mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF- alpha that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumour activity and reduced systemic toxicity in mice compared with murine TNF- alpha, which binds to both murine TNF receptors. Based on these results, many TNF- alpha mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumour cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF- alpha High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.