125 Results for: "Respiratory Protection"

Supplier: ProSci Inc.

Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulphide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell signalling. Furthermore, Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury. This protein is mainly expressed in neutrophils and in lower levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts. Recent evidence also suggests its role as a biomarker for renal injury and inflammation.

Supplier: ProSci Inc.

Alpha-1 Antitrypsin or alpha1-antitrypsin (A1AT) is a protease inhibitor belonging to the serpin superfamily. It is generally known as serum trypsin inhibitor. Alpha 1-antitrypsin is also referred to as alpha-1 proteinase inhibitor (A1PI) because it inhibits a wide variety of proteases. It protects tissues from enzymes of inflammatory cells, especially neutrophil elastase, and has a reference range in blood of 1.5 - 3.5 gram/liter (in US the reference range is generally expressed as mg/dL or micromoles), but the concentration can rise manyfold upon acute inflammation. In its absence (such as in alpha 1-antitrypsin deficiency), neutrophil elastase is free to break down elastin, which contributes to the elasticity of the lungs, resulting in respiratory complications such as emphysema, or COPD (chronic obstructive pulmonary disease) in adults and cirrhosis in adults or children.

Like all serine protease inhibitors, A1AT has a characteristic secondary structure of beta sheets and alpha helices. Mutations in these areas can lead to non-functional proteins that can polymerise and accumulate in the liver (infantile hepatic cirrhosis). [Wiki].

Supplier: ProSci Inc.

Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.

Supplier: ProSci Inc.

Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.

Supplier: ProSci Inc.

Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.

Supplier: MP Biomedicals

Storage: +4 °C
Pyruvic acid is an intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. It improves coliform recovery when present in culture medium. It is involved in a metabolic regulatory pathway activated by mitochondrial oxidants. Pyruvate is involved in respiratory regulation in plants by interacting with alternative oxidase at a conserved cysteine residue. It may help prevent hydrogen peroxide mediated cell death.
Sodium pyruvate is utilized as a component in culture broth and media. Sodium pyruvate is used in Wallen fermentation medium to enhance the conversion of oleic acid to 10-ketostearic acid by Bacillus sphaericus. Sodium pyruvate has also been used to establish stably transfected human B cell lines.
Sodium Pyruvate has shown antioxidant properties and protective effects against oxygen radicals. Pyruvate is produced as part of glycolysis and is an intermediate in many metabolic pathways. It can be converted into acetyl CoA and enter the TCA Cycle.

Supplier: JSP

The PowerCap® Active™ is a lightweight positive pressure respirator with eye and face protection, as well as EN812 bumpcap protection. Designed to protect the user from dust and most airborne particulate pollutants to EN12941 TH1P.

Supplier: 3M

The Versaflo™ Over-Visor, gold, IR/UV shade 5, M-967, is an over-visor to protect against UV/IR, metal sparks, and splashes.

Supplier: 3M

The Versaflo™ Filter Cover TR-6500FC is a filter cover that helps to protect Versaflo™ TR-6580E filters from physical damage.

Supplier: 3M

Versaflo™ Spark Arrestor TR-362 is an accessory designed to protect the filter and turbo in Versaflo™ Powered Air Turbo TR-300+.

Supplier: 3M

The Versaflo™ Headtop Cover M-972 is a flame-resistant polyester headtop cover designed to protect the M-Series headtop from sparks and hot particles.

Supplier: 3M

The Versaflo™ Filter Cover TR-6300FC is a filter cover which helps protect 3M™ Versaflo™ TR-6310E filter from physical damage.

Supplier: 3M

The Versaflo™ Filter Cover TR-6100FC is a filter cover to help protect Versaflo™ TR-6110E and TR-6130E filters from physical damage.

Supplier: 3M

The Versaflo™ Peel-Off Visor Cover M-928 is an easy-to-use, transparent, self-adhesive visor cover designed to protect 3M™ Versaflo™ M-Series Headtop visors from scratches and overspray of paint or chemicals.

Supplier: JSP

Dust and half masks commonly fail to do the job they are intended to do because of poor fitting and care by the user. Qualitative Fit Testing can be used not only as a test method to ensure wearers are properly protected, but also as a very effective way of training them in the correct way of fitting a mask.

Supplier: 3M

These Versaflo™ Radiant Heat Covers are made from lightweight, aluminised aramid fabric and provide improved head, neck, and shoulder protection and comfort from radiant heat. The covers are designed for use with Versaflo™ helmets M-307 and M-407.

Supplier: 3M

3M™ Versaflo™ V-Series supplied air regulators offer protection against dust, mist, fumes, gases or vapours and combination hazards e.g. paint spray. Supplied air regulators do not offer protection in confined spaces, oxygen deficient atmospheres or for asbestos stripping. The 3M™ Versaflo™ V-500E supplied air regulator is a balanced, belt-worn, easy to adjust regulator specifically designed to ensure smooth airflow, safety and comfort.

Supplier: 3M

Versaflo™ S Series Peel-Off Visor Covers are transparent, peel-off visor covers designed for use with Versaflo™ Series S-133, S-333, S-433, and S-533 head covers and hoods. This self-adhesive cover protects the visor from contaminants and scratches.

Supplier: 3M

This range provides lightweight, effective, comfortable and hygienic protection from dust and aerosols.

Supplier: 3M

Unique FFP3 respirator with two-way protection and added exhalation valve for comfort.

Supplier: VWR Collection

These masks provide protection against particulates, dust and aerosols. For use against non toxic to low toxicity solid and liquid aerosols.

Supplier: THI Total Healthcare Innovation GmbH

Sterile full headcover system with active air filtration to protect your cleanroom and provide user comfort.

Supplier: 3M

3M™ Aura™ Particulate Respirators 9300+ Series has an ergonomic, flat-fold, 3-panel design featuring a low breathing resistance filter media. Available in FFP1, FFP2, and FFP3 protection levels, and with valved and unvalved models, these respirators feature an innovative chin tab for easy adjustments and an embossed, sculpted upper panel to help reduce eyewear fogging.

Supplier: Dräger

This combined fire and industrial escape hood was developed with users, placing the focus on the fastest possible escape. Optimised operation and wearing comfort, a robust housing and a tested ABEK P3 filter ensure protection from toxic industrial gases, vapours and particles for at least 15 minutes.

Supplier: 3M

Head, neck and shoulder protection white for outdoors

Supplier: 3M

Replacement inner collar for use with the Versaflo™ M-400 Headtop. The inner collar zips into the shroud and provides a comfortable respiratory seal.

Supplier: Dräger

This combined fire and industrial escape hood was developed with users, placing the focus on the fastest possible escape. Optimised operation and wearing comfort, a robust housing and a tested ABEK CO P3 filter ensure protection from toxic industrial and fire-related gases, vapours and particles for at least 15 minutes.

Supplier: Dräger

The powered air-purifying respirator (PAPR) X-plore 8000 offers a number of user friendly standard and specialised carrying systems for standard and decontamination applications. Dräger has also developed a wide range of tight- and loose-fitting headgear such as half and full-face masks, short and long hoods and helmets with visor and protective visor. Standard and enhanced flexibility hoses are available and compatibility is ensured. Modular components: A wide range of components for every application.

Supplier: Portwest

This mask with valve protects against a high concentration of dust, water based mist and fumes.

Supplier: Medicom

Designed to protect against high risk infectious diseases, these filtering half masks provide FFP2 NR D class protection against solid and liquid aerosols.