"Other Essentials"

Supplier: Bioss

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC); as well as in the fragmentation of the Golgi apparatus during mitosis.

Supplier: Abcam

MMP3 (Stromelysin-1) inhibitor. Additionally shows broad spectrum inhibition activity at other MMPs. Cell permeable.

Supplier: CERTOCLAV

Log printer (for document and archive the sterilisation cycles during sterilisation)

Supplier: AAT Bioquest

Biotinylated horse radish peroxidase (HRP) is an excellent tool for biological detections with ELISA and other enzyme-coupled assays.

Supplier: Ansell

These sleeves contain a very high proportion of Dyneema® fibres which are as strong as steel fibres but much lighter and more flexible.

Supplier: LIEDER JOHANNES

The slides are arranged and compiled, so that each enlarges the subject line of the proceeding one.

Supplier: ProSci Inc.

Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a 179 amino acid enzyme that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2C is highly expressed in tumour tissues and at low levels in most adult normal tissues. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C accepts Ubiquitin from the E1 complex and catalyses its covalent attachment to other proteins. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), which has E3 ubiquitin ligase activity, and targets for destruction substrates from the preceding mitosis (Cyclin A, Cyclin B, Securin, Geminin).

Supplier: Bioss

Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Supplier: Bioss

Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Supplier: Bioss

Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Supplier: Sartorius Balances

Cubis® II MCE semi-micro balances with essential user interface offer readability of 10 µg and a maximum weighing capacity up to 220 g. Used for weighing small sample amounts down to the µg-range.

Supplier: MERCK PRODUCTION CHEMICALS

Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present.
Corresponds to Ph Eur, BP, USP, FCC, JP, E 500
Conforms to the purity criteria on food additives according to the current European Commission Regulation.

Supplier: MERCK PRODUCTION CHEMICALS

Disodium hydrogen phosphate dodecahydrate, EMPROVE® ESSENTIAL BP, Ph. Eur., JP, USP suitable for use as excipient, SAFC®

Supplier: HyClone products (Cytiva)

HyClone AdvanceSTEM ES Qualified Amino Acids have been optimized for growth of embryonic cell cultures.

Supplier: Bioss

Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).

Supplier: Bioss

Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).