Supplier: KEYSTONE CLEANROOM PRODUCTS

Tyvek® 1073B/HDPE autoclave bags are ideal for steam sterilisation of pharmaceutical components such as vial and syringe stoppers and caps. Also a good choice for heavy equipment parts where visibility into the bag is required.

Supplier: Bioss

KLHL28 is a 571 amino acid protein similar to the Drosophila kelch protein. KLHL26 contains six kelch repeats and one BTB (POZ) domain. The BTB (broad complex, tramtrack and bric-a-brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL28 is expressed as two isoforms produced by alternative splicing.

Supplier: Bioss

BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

Supplier: Bioss

BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

Supplier: KEYSTONE CLEANROOM PRODUCTS

Protect your filling needles from accidental touching after they are removed from the primary sterilisation packaging. Also creates secondary level of protection during aseptic presentation.

Supplier: Heidolph Instruments GmbH & Co.KG

The Hei-VAP ultimate, precise setting of rotation speed and heating bath temperature on the digital touch display or for quick access during an active process directly via the knobs on the operating panel.

Supplier: Bioss

KLHL28 is a 571 amino acid protein similar to the Drosophila kelch protein. KLHL26 contains six kelch repeats and one BTB (POZ) domain. The BTB (broad complex, tramtrack and bric-a-brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL28 is expressed as two isoforms produced by alternative splicing.

Supplier: Bioss

KLHL28 is a 571 amino acid protein similar to the Drosophila kelch protein. KLHL26 contains six kelch repeats and one BTB (POZ) domain. The BTB (broad complex, tramtrack and bric-a-brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL28 is expressed as two isoforms produced by alternative splicing.

Supplier: Trajan Scientific and Medical

The SGE BPX5 GC Capillary Column provides a great low-polarity option for GC analyses. Recommended for: Ultra trace analyses, pesticides, herbicides, hydrocarbons, solvents, phenols, amines.

Supplier: Brady

These B-595 vinyl labels will adhere to difficult low surface energy items, including: PVC piping, blow-molded equipment cases, ABS plastics, powder-coated surfaces and equipment made from recycled plastics.

Supplier: Abeba

ESD shoe made from smooth or perforated leather with non foldable, adjustable heel strap and a rubber sole (resistant to fuels, oils, acids and bases).

Supplier: Bioss

BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

Supplier: THERMO BIOPROCESS DIVISION

BioProcess Container™ (BPC™) systems include two-dimensional single-use bags for liquid handling. Manufactured from medical-grade plastics (cGMP compliant) and configured with ports, tubing and fittings, BPC™ systems provide an efficient means for sterile liquid handling in research and production settings.

Supplier: Thermo Fisher Scientific

Using advanced low-retention technology, the hydrophobic inner surface of these tips significantly reduces sample loss to adhesion and maximises sample recovery. The tips are suitable for use when working with the most difficult samples, such as radioactive compounds, viscous materials, fragile cell lines, viruses, difficult proteins and PCR reagents.

Supplier: MILLIPORE

Nylon filters are compatible with a broad range of solvents. Two types of filters are available, membrane filters with pore sizes ranging from 0,20 to 1,20 µm and woven net filters with mesh openings ranging from 10 to 180 µm.

Supplier: Ahlstrom-Munksjö

Ahlstrom-Munksjö offers a full range of high quality cotton papers with high absorbency – ideal for chromatographic analysis and blotting methods with gel (Southern, Northern and Western Blots). Ahlstrom-Munksjö manufactures, both in Europe and in the US, absorbent papers made of the highest purity cotton linters. These media do not contain additive of any kind, thus preventing any contamination during the transfer steps.

Supplier: Avantor

Avantor® ACE® Excel® SuperC18 columns provide high stability across an extended pH range. These stainless steel columns are ideal for use with LC/MS compatible buffers and can be used with both MeOH and MeCN mobile phases.

Supplier: Avantor

Avantor® ACE® C18 columns provide great reproducibility and column lifetime. These stainless steel columns are available in a wide range of particle sizes and dimensions from capillary to preparative.

Supplier: VWR Collection

Designed for the preparation of buffers, tissue culture media, microbiological media and other biological fluids. These vacuum filtration systems feature large diameter high performance PES membranes for guaranteed performance and maximum throughput. The full assembly includes a filtration unit and a receiver bottle with an ergonomic shape, moulded finger grips and a patented bottle cap. The centrifuge tube and funnel system allows the user to filter fluids directly into a 15 or 50 ml tube.

Supplier: KEYSTONE CLEANROOM PRODUCTS

Tyvek® 1073B bags are ideal for steam sterilisation of pharmaceutical components such as vial and syringe stoppers and caps as well as heavy equipment parts with sharp edges.

Supplier: Bioss

BTBD14A is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

Supplier: Bioss

KLHL28 is a 571 amino acid protein similar to the Drosophila kelch protein. KLHL26 contains six kelch repeats and one BTB (POZ) domain. The BTB (broad complex, tramtrack and bric-a-brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL28 is expressed as two isoforms produced by alternative splicing.

Supplier: VWR Collection

PS, transparent, graduated, non sterile or sterile. These disposable pipettes for liquid transfers are made of GPPS (general polystyrene), in compliance with USP Class VI.

Supplier: VWR Collection

These mats offer the comfort of a polyurethane mat which is suitable for ISO Class 5 cleanroom (Class 100) environments. It is either available with a bubble surface, that features a unique ergonomic and anti-fatigue design, or with a smooth surface that is ideal for areas that combine sitting and standing.

Supplier: VWR Collection

Square PETG bottles are ideal for storage of media, laboratory reagents and biological buffers up to −70 °C. Eliminate washing, depyrogenation and autoclaving steps with sterile and non-pyrogenic.

Supplier: VWR Collection

Safe-T-Flex caps feature a unique, flexible, over-locking design, locking securely on the outside of the tube lip and can be removed with one hand. A tight seal ensures sample integrity and prevents spillage or evaporation of serum samples. This special seal protects against the aerosols of highly infectious organisms such as TB and the HTLV-III virus. They are colour coded for easy specimen identification and to help guard against cross-contamination. The top of each cap can also be numbered or labelled with indelible ink. Self-locking cap holds firmly in any position and keeps contents secure while in transit. Liquid-tight seal withstands centrifugation, agitation, refrigeration and freezing.

Supplier: ROBU GLASFILTER

VitraPOR® glass filters are precision-engineered porous glass components for effective filtration in laboratory and industrial settings.

Supplier: Bioss

Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN. Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C). In contrast, it does not deubiquitinate PLK1. Specifically deubiquitinates MYC in the nucleoplasm, leading to prevent MYC degradation by the proteasome: acts by specifically interacting with isoform 1 of FBXW7 (FBW7alpha) in the nucleoplasm and counteracting ubiquitination of MYC by the SCF(FBW7) complex. In contrast, it does not interact with isoform 4 of FBXW7 (FBW7gamma) in the nucleolus, allowing MYC degradation and explaining the selective MYC degradation in the nucleolus.

Supplier: Bioss

Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation. Mediates MYC-mediated let-7 repression. Isoform 1, when overexpressed, stimulates growth of the breast adenocarcinoma cell line MCF-7. Isoform 2 has no effect on cell growth.

Supplier: VARIAN

The PLRP-S family of products consists of a range of pore sizes and particle sizes, all with identical chemistry and fundamental adsorptive characteristics. The particles are inherently hydrophobic so there is no bonded phase, alkyl ligand required for reversed-phase separations. This gives a highly reproducible material that is free from silanols and heavy metal ions. Within the extensive product range are columns suitable for analytical separations and preparative purifications.