Supplier: Bioss

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.

Supplier: Bioss

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.

Supplier: VWR Collection

Headspace ND18 vials with screw neck manufactured from 1st hydrolytic class borosilicate glass with a round bottom. They can be purchased with a variety of magnetic aluminium screw caps and septa materials.

Supplier: Bioss

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.

Supplier: Bioss

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.

Supplier: Bioss

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.

Supplier: Bioss

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.

Supplier: Bioss

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.

Supplier: Bioss

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.

Supplier: Avantor

Avantor® ACE® AQ columns provide great reproducibility and column lifetime. These stainless steel columns are available in a wide range of particle sizes and dimensions from capillary to preparative.

Supplier: FRISTADS KANSAS

Durable sweatshirt made of 65% polyester and 35% cotton.

Supplier: Avantor

These ultra-inert Avantor® ACE® C8 columns provide great reproducibility and column lifetime. These stainless steel columns are available in a wide range of particle sizes and dimensions from capillary to preparative.

Supplier: NEW PIG

No more lugging around large rolls of mat, let this vertical mat roll holder do all the work.

Supplier: ProSci Inc.

ULK2 Antibody: ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.

Supplier: KEYSTONE CLEANROOM PRODUCTS

PureClean™ self-sealing autoclave bags are made from a transparent film and 1421B DuPont™ Tyvek®, which is a new grade of uncoated, untreated, flexible Tyvek® material specifically designed for pharmaceutical use in steam sterilisation applications. Uncoated Tyvek® eliminates the potential of residue deposits on equipment, post sterilisation.

Supplier: SIOEN

Multifunctional and anti-static ARC trousers that provide excellent protection against arcs, heat, and metal splashes.

Supplier: DWK Life Sciences

The Wheaton® R2P™ 2.0 roller culture apparatus is designed to allow for the development and growth of cultured cells from research to production quantities without having to change equipment and revalidate protocols. The R2P™ 2.0 system utilises computerised measurement of the actual bottle speed and allows networking for up to 255 units. Applications include, Viruses for vaccines or related studies, proteins, enzymes, antibodies, live cell assays.

Supplier: Thermo Scientific

Designed for everyday laboratory needs the Thermo Scientific™ TSG series general purpose laboratory freezers are designed with your needs in mind. The TSG series range of freezers feature the performance, security, and quality required for your laboratory applications.

Supplier: Aesculap

Bone curette with PEEK-handle, Fig. 2, with 8,5 mm end, Aesculap®

Supplier: VWR Collection

30 or 60 layer adhesive entrance mats manufactured from low density polyethylene. These mats control contamination by removing debris from the soles of shoes, and the wheels of transport containers. When one layer is dirty, simply remove by the numbered corner tab, leaving a fresh layer ready for use.

Supplier: VWR Collection

Headspace ND20 vials with crimp neck manufactured from 1st hydrolytic class borosilicate glass in both flat bottom and round bottom style. They can be purchased with a variety of aluminium seal styles and septa materials.

Supplier: Air Liquide

These vessels are designed for long term storage of biological samples in straws, cryo-vials and bags. A variety of electronic options on all models rack or canister storage systems for the samples.
Made of aluminum and composite materials.

Supplier: VWR Collection

These trousers are manufactured from 99% polyester fibres and 1% Hydro-Tec fibres. The special fabric, with Hydro-Tec nanotechnology finish, makes the trousers extremly durable and provides anti-static features as well as protection against dirt, oil, chemicals and water.

Supplier: ENTEGRIS

These filters are designed to consistantly remove particles from a whide range of acids, bases and other process materials. Ideal for medium to high flow applications, they deliver a low cost of ownership (COO) as a dry device or prewet product ready for quick installation. Prewet cartridges prevent alcohol-chemical interactions, avoid potential contamination sources and minimise process downtime.

Supplier: KEYSTONE CLEANROOM PRODUCTS

Self-sealing Tyvek® 1073B bags are ideal for steam sterilisation of pharmaceutical components such as vial and syringe stoppers and caps as well as heavy equipment parts with sharp edges. No need to use or validate a heat sealing machine.

Supplier: Corning

Axygen MaxyClear polypropylene microcentrifuge tubes feature exceptional clarity without compromising on strength.

Supplier: Hettich

The Hettich EBA 270 is a compact benchtop centrifuge for the clinical laboratory.

Supplier: FRISTADS KANSAS

Vest made from 65% polyester and 35% cotton; napped inner.

Supplier: FRISTADS KANSAS

Water repellent trousers made of polyester and cotton. The reinforcement is made of 100% polyamide.

Supplier: CHIRAL TECHNOLOGIES

These columns allow chromatographers to employ essentially any organic solvent as mobile phase to develop methods for the most challenging separations. These columns are available in a variety of particle sizes and offer great speed and column resolving power. Columns packed with 3 µm CSPs offer high speed separations and a reduction in analysis time and cost per sample. Columns, packed with 3 µm particles, may be used in conventional HPLC units without significant loss in performance, even with the smaller column dimensions.