49550 Results for: "Microscopy+Control+Slides&pageNo=8"

S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly by directly binding to NCF2/P67PHOX. The extracellular functions involve proinfammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its proinflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to pattern recognition receptors such as Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). Binding to TLR4 and AGER activates the MAP-kinase and NF-kappa-B signaling pathways resulting in the amplification of the proinflammatory cascade. Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn(2+) which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect; regulates cell survival via ITGAM/ITGB and TLR4 and a signaling mechanism involving MEK-ERK.

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Human GPR182 ELISA Kit

Supplier: Antibodies.com

Human GPR182 ELISA Kit

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Basket Trolleys

Supplier: HUPFER METALLWERKE

Basket transport trolleys in high version for empty and loaded 500×500 mm crockery baskets.

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Human NOX2/Gp91phox ELISA Kit

Supplier: Antibodies.com

Human NOX2/Gp91phox ELISA Kit

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BOTTLE 15ML AMBER NM DIN 18 1 * 152 items

Supplier: GRAVIS

BOTTLE 15ML AMBER NM DIN 18 1 * 152 items

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BIB N' BRACE 1075 ATHS YELLOW/NAVY 58 1 * 1 items

Supplier: FRISTADS KANSAS

BIB N' BRACE 1075 ATHS YELLOW/NAVY 58 1 * 1 items

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Orthophosphoric acid ≥85%, pure analytical reagent

Supplier: POCH AVANTOR BRAND

Orthophosphoric acid ≥85%, pure analytical reagent

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GFP-tagged ORF clone of Homo sapiens suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) (ST18) as transfection-ready DNA 1 * 10 µG

Supplier: OriGene

GFP-tagged ORF clone of Homo sapiens suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) (ST18) as transfection-ready DNA 1 * 10 µG