Supplier: Merck

Cobalt(II) chloride hexahydrate, EMSURE® ACS, Reag. Ph. Eur. for analysis, Supelco®

Supplier: AAT Bioquest

Gentamicin is widely used for treating tuberculosis and Gram-negative infections and is particularly useful in neonatal intensive care units. Fluorophore-tagged drugs, such as gentamicin-Texas Red (GTTR) conjugates, have been used to identify drug trafficking routes across the BLB and into hair cells, and specifically in the cochlea - the sensory organ responsible for hearing. Identifying the mechanisms involved in the intracochlear trafficking of ototoxic drugs to hair cells is of fundamental as well as clinical importance. Texas Red-gentamicin conjugate (GTTR) provides researchers a valuable tool to study the cellular uptake, kinetics and distribution of gentamicin through fluorescence techniques, such as fluorescence microscopy, fluorescence correlation spectroscopy, single molecule spectroscopy. The TR fluorophore can be conveniently excited from 500-600 nm, with an emission maximum centered around 610 nm. Acute nephrotoxicity and permanent ototoxicity are serious side-effects that increase patient morbidity, or induce permanent auditory and vestibular deficits. Several approaches have been used to study the intracellular mechanisms induced by ototoxic drugs. However, ototoxic drugs must first cross the blood-labyrinth barrier (BLB) before entering sensory hair cells to exert their cytotoxic effect that leads to hearing loss and deafness. The BLB is similar to the blood-brain barrier (BBB), and is composed of tight junction-coupled endothelial and epithelial barrier layers that transport nutrients and ions from one side of the barrier to the other.

Supplier: ProSci Inc.

Anti-PRDM9 Recombinant Antibody [Clone: RAB-C370]

Supplier: Honeywell Chemicals

Sodium nitroprusside dihydrate ≥99% ACS, Fluka™

Supplier: Abcam

Rabbit polyclonal to NMDAR1 (phospho S897).

Supplier: Honeywell Chemicals

Cobalt(II) chloride hexahydrate 98-102%, Puriss. p.a. ACS, Reag. Ph. Eur., Fluka™

Supplier: Abcam

Rabbit polyclonal to MBD3.

Supplier: Abcam

Rabbit monoclonal [EPR3564] to MBD1.

Supplier: VWR Chemicals

Tetrasodium diphosphate decahydrate 99.0-103.0%, AnalaR NORMAPUR® ACS, Reag. Ph. Eur. analytical reagent

Supplier: ProSci Inc.

Anti-PRDM9 Recombinant Antibody [Clone: RAB-C370]

Supplier: Thermo Fisher Scientific

Cadmium(II) sulphate 8/3-hydrate 98.0-102.0% ACS

Supplier: Abcam

Mouse monoclonal [5MC-CD] to 5-methylcytosine (5-mC).

Supplier: Abcam

Rabbit monoclonal [EPR2480Y] to NMDAR1 - Neuronal Marker.

Supplier: Abcam

Rabbit monoclonal [EPR7063] to NMDAR2A.

Supplier: Merck

Copper(II) sulphate pentahydrate, EMSURE® ISO, ACS, Reag. Ph. Eur. for analysis, Supelco®

Supplier: Honeywell Chemicals

Copper(II) sulphate pentahydrate 99-102%, Puriss. p.a. ACS, ISO, Reag. Ph. Eur., Fluka™

Supplier: Thermo Fisher Scientific

Cadmium(II) sulphate 8/3-hydrate, crystals ACS

Supplier: Cytiva (Formerly Pall Lab)

These devices are used for simple, reliable concentrating and desalting of 50 to 500 μl samples. Select the low protein binding Omega™ membrane for ultrafiltration applications. The Bio-Inert® membrane is ideal for microfiltration of biological solutions. The GHP membrane is ideal for sample preparation in analytical chemistry (HPLC, GC, IC and MS). It is suitable for aqueous, organic and aggressive organic samples, and for rapid processing of samples.

Supplier: Abcam

Mouse monoclonal [33D3] to 5-methylcytosine (5-mC).

Supplier: Abcam

Rabbit polyclonal to NMDAR2B (phospho S1480).

Supplier: Abcam

Rabbit polyclonal to NMDAR1.

Supplier: Brady

Make labels that withstand up to 10 years of outdoor abuse with this low-shrink vinyl label material (B-595). Print almost anywhere with a durable Brady handheld label maker.

Supplier: Antibodies.com

Rabbit polyclonal antibody to GRIN2D for WB and ELISA with samples derived from Human, Mouse and Rat.

Supplier: Antibodies.com

Rabbit polyclonal antibody to NMDAepsilon4 for IHC and ELISA with samples derived from Human, Mouse and Rat.

Supplier: OMEGA BIO-TEK

Isolate DNA from molluscs and insects using spin columns.

Supplier: Thermo Fisher Scientific

Sodium nitroprusside dihydrate 99.0-102.0% ACS

Supplier: Avantor

General purpose low to mid polarity phase for a wide range of applications, including (for example): Residual solvents, volatile pollutants. HI-624 MS is an MS grade cross-bonded column.

Supplier: Thermo Fisher Scientific

Chromium(III) potassium sulphate dodecahydrate 98.0-102.0% ACS

Supplier: Ansell

These fully coated gloves feature a PU foam insulation for additional warmth and comfort. The textured surface provides unbeatable grip on wet and slippery surfaces. The robust, liquid-repellent PVC coating does not absorb water, does not stiffen like leather and remains flexible even in sub zero temperatures.

Supplier: Thermo Fisher Scientific

The Hydrophilic Interaction Liquid Chromatography (HILIC) technique offers complementary selectivity to reversed phase. With the ability to retain highly polar and hydrophilic compounds, these columns have been developed to aid the analysis of compounds that are traditionally difficult to retain using conventional C18 columns.