52109 Results for: "Intrinsic+factor"

Supplier: Bioss

When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

Supplier: Bioss

When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

Supplier: Bioss

When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

Supplier: Bioss

Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

Supplier: Abcam

Recombinant Mouse FLT1/VEGF Receptor 1 protein (Active) is a Mouse Fragment protein, in the 23 to 759 aa range, expressed in HEK 293, with ≥95% purity, ≤0,005 EU/µg endotoxin level and suitable for SDS-PAGE.

Supplier: Bioss

When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

Supplier: Abcam

Recombinant mouse TRAP/CD40L protein (Active) is a Mouse Fragment protein, in the 115 to 260 aa range, expressed in HEK 293, with >95% purity, <1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS, ELISA, HPLC.

Supplier: Bioss

When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

Supplier: Abcam

Recombinant Human SMARCA2 / BRM protein (Tagged) is a Human Fragment protein, in the 700 to 1216 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.

Supplier: Abcam

Recombinant mouse Peroxiredoxin 1/PAG protein (Active) is a mouse full length protein, in the 1 to 199 aa range, expressed in Baculovirus infected insect, with >90% purity, <1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.

Supplier: Bioss

MCM3 is one of the highly conserved mini-chromosome maintenance proteins that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

Supplier: Bioss

The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair.

Supplier: Bioss

When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

Supplier: Abcam

Recombinant Human KAP1 protein is a Human Full Length protein, in the 1 to 835 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.

Supplier: Abcam

Recombinant human Fas Ligand protein is a Human protein, in the 103 to 281 aa range, expressed in HEK 293, with >95% purity, >0,1 EU/µg endotoxin level and suitable for SDS-PAGE, ELISA, WB, FuncS.

Supplier: Abcam

Recombinant Mouse TL1A protein is a Mouse Fragment protein, in the 94 to 252 aa range, expressed in HEK 293, with >95% purity, <0.1 EU/µg endotoxin level and suitable for SDS-PAGE, ELISA, Flow Cyt.

Supplier: Bioss

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.

Supplier: Bioss

Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).

Supplier: Abcam

Recombinant Human TRAP/CD40L protein (Fc Chimera) is a Human Full Length protein, in the 113 to 261 aa range, expressed in CHO, with ≥98% purity, <0.06 EU/µg endotoxin level and suitable for SDS-PAGE.

Supplier: Abcam

Recombinant Human CD134/OX40L receptor protein (His tag) is a Human Fragment protein, in the 51 to 183 aa range, expressed in HEK 293, with >90% purity, <1 EU/µg endotoxin level and suitable for SDS-PAGE.

Supplier: Abcam

Recombinant Human PLA2G7 protein is a Human Full Length protein, in the 22 to 441 aa range, expressed in HEK 293, with >95% purity, <1 EU/µg endotoxin level and suitable for SDS-PAGE, HPLC.

Supplier: Abcam

Recombinant Human TRAP/CD40L protein (Soluble) is a Human Full Length protein, in the 113 to 261 aa range, expressed in HEK 293, with >95% purity, <1 EU/µg endotoxin level and suitable for SDS-PAGE, HPLC.

Supplier: Abcam

Recombinant human DR5 protein is a human fragment protein, in the 52 to 212 aa range, expressed in HEK 293, with >95% purity, <0,1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.

Supplier: Abcam

Recombinant human/mouse TGF beta 3 protein (Animal Free) is a Human Full Length protein, in the 301 to 412 aa range, expressed in Escherichia coli, with >95% purity, ≤1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.

Supplier: Abcam

Recombinant human HBEGF/DTR protein (Animal Free) is a Human Full Length protein, in the 63 to 148 aa range, expressed in Escherichia coli, with >97% purity, <0,05 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.

Supplier: Abcam

High activity fusion construct of human soluble TRAP/CD40L is a Human protein, in the 116 to 261 aa range, expressed in CHO, with >90% purity, <0,1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.

Supplier: Abcam

Recombinant EGFR (mutated P753S & del747-752) protein (Active) is a Human Fragment protein, in the 695 to 1210 aa range, expressed in Baculovirus infected Sf9, with >90% purity and suitable for SDS-PAGE, FuncS.

Supplier: Abcam

PE Mouse monoclonal [DR5-01-1] to DR5.

Supplier: Abcam

Recombinant Human ADI1 protein is a Human Full Length protein, in the 1 to 179 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.

Supplier: Abcam

Recombinant Human BRG1 protein (denatured) is a Human Fragment protein, in the 362 to 549 aa range, expressed in Escherichia coli, with >80% purity and suitable for SDS-PAGE.