51370 Results for: "Intrinsic+factor"

Supplier: Abcam

Sheep polyclonal to Factor VIII.

Supplier: Abcam

Sheep polyclonal to Factor Va.

Supplier: Bioss

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Supplier: Abcam

Anti-Factor XIa Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Factor XIII Sheep Polyclonal Antibody

Supplier: Bioss

Anti-factor XIII Rabbit Polyclonal Antibody

Supplier: Apollo Scientific

Human recombinant Hypoxia-Inducible Factor-1 alpha

Supplier: US Biological

Anti-Platelet Factor 4 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Trefoil Factor 2 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Osteoinductive Factor Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Coagulation factor IX（F9), is a member of the peptidase S1 family. It contains two EGF-like domains, a Gla domain and a peptidase S1 domain. It is primarily expressed in the liver and secreted in plasma. Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa. Mutations in position 43 and 46 prevents cleavage of the propeptide, mutation in position 93 probably fails to bind to cell membranes, mutation in position 191 or in position 226 prevent cleavage of the activation peptide. Mutations of human F9 can result in thrombophilia and recessive X-linked hemophilia B (HEMB). An X-linked blood coagulation disorder characterized by a permanent tendency to hemorrhage, due to factor IX deficiency. It is phenotypically similar to hemophilia A, but patients present with fewer symptoms. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma.

Supplier: US Biological

Anti-Factor Va Sheep Polyclonal Antibody

Supplier: US Biological

Anti-Transcription Factor 7 Goat Polyclonal Antibody

Supplier: US Biological

Anti-Trefoil Factor 3 Rabbit Polyclonal Antibody

Supplier: Abcam

Anti-Factor XII Goat Polyclonal Antibody

Supplier: US Biological

Anti-Complement Factor H Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Tissue Factor Mouse Monoclonal Antibody

Supplier: Bioss

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Supplier: US Biological

Anti-Thymic Factor Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Osteoinductive Factor Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Complement Factor D Goat Polyclonal Antibody

Supplier: US Biological

Anti-Nuclear Factor I/C Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Steroidogenic Factor 1 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Steroidogenic Factor 1 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Splicing Factor 4 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Platelet Factor 4 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Trefoil Factor 3 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Trefoil Factor 3 Rabbit Polyclonal Antibody

Supplier: Abcam

Rabbit monoclonal [EPR6225] to Factor H.

Supplier: Bioss

Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.