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Pifithrin-α hydrobromide ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Suppresses self-renewal of embryonic stem cells.

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BML-210 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

HDAC inhibitor developed at Enzo Life Sciences. Inhibits HDAC activity in HeLa nuclear extracts (IC50=5-10µM).

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scriptaid ≥97% (by TLC)

Supplier: ENZO LIFE SCIENCES

HDAC inhibitor

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[Ser25]-Protein kinase C (19-31)

Supplier: ENZO LIFE SCIENCES

PKC substrate

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(S)-2-Amino-5-guanidino-N-(4-nitrophenyl)pentanamide dihydrochloride ≥99%

Supplier: ENZO LIFE SCIENCES

Aminopeptidase substrate

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AM 580 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Retinoic acid analog which acts as a selective RARα agonist with no affinity for RXRs. Induces differentiation in leukemia cell lines and inhibits angiogenesis in chick embryos.

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FLUOR DE LYS®-succinyl green, desuccinylase substrate 5 mM in DMSO (synthetic) , 95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

The FLUOR DE LYS®-Succinyl green, desuccinylase substrate offers a highly sensitive and convenient alternative to radiolabeled, succinylated histones or peptide/HPLC methods for the assay of desuccinylases such as SIRT5.

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Leukotriene A4 methyl ester ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Substrate for LTA₄ hydrolase and LTC₄ synthase.

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Lysophosphatidic acid ≥98% (by TLC)

Lysophosphatidic acid ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

LPA receptor ligand

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Leukotriene E4-20,20,20-d3 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Prostanoid receptor ligand.

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N-Palmitoyl phosphatidylethanolamine ≥98% (by TLC), white solid

Supplier: ENZO LIFE SCIENCES

Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice (100 mg/kg, i.p.), without causing taste aversion. Has been found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations). This suggests that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight.

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Despropionylfentanyl ≥99% (by HPLC)

Supplier: ENZO LIFE SCIENCES

A major urinary metabolite of fentanyl.

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12(S)-Hydroperoxyeicosa-5Z,8Z,10E,14Z-tetraenoic acid (HPETE) ≥98%

Supplier: ENZO LIFE SCIENCES

Primary metabolite of arachidonic acid via the 12-lipoxygenase pathway. Inhibits thromboxane synthase. Inhibits platelet aggregation via activation of guanylate cyclase (100% at 5µM). Stimulates leukotriene biosynthesis. Potent and selective inhibitor of Ca2+-calmodulin-dependent protein kinase II (IC50=0.7µM). Endogenous TRPV1 agonist (Ki=0.35µM).

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15-Ketoeicosa-6E,8Z,11Z,13E-tetraenoic acid ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Biosynthesis via 15-OH prostaglandin dehydrogenase from lung and liver microsomes and by a nonenzymatic process.

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α-Hydroxytriazolam ≥96% (by TLC)

α-Hydroxytriazolam ≥96% (by TLC)

Supplier: ENZO LIFE SCIENCES

An active but short-lived metabolite of triazolam.

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PROTEASOME 19S RPT5/S6A SUBUNIT MONOCLONAL ANTIBODY (TBP1-19) 1 * 100 µl

Supplier: ENZO LIFE SCIENCES

PROTEASOME 19S RPT5/S6A SUBUNIT MONOCLONAL ANTIBODY (TBP1-19) 1 * 100 µl

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PROTEASOME 19S RPT2/S4 SUBUNIT (YEAST) POLYCLONAL ANTIBODY 1 * 25 µl

Supplier: ENZO LIFE SCIENCES

PROTEASOME 19S RPT2/S4 SUBUNIT (YEAST) POLYCLONAL ANTIBODY 1 * 25 µl

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PROTEASOME 19S RPT3/S6B SUBUNIT MONOCLONAL ANTIBODY (TBP7-27) 1 * 25 µl

Supplier: ENZO LIFE SCIENCES

PROTEASOME 19S RPT3/S6B SUBUNIT MONOCLONAL ANTIBODY (TBP7-27) 1 * 25 µl

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PROTEASOME 19S RPT4/S10B SUBUNIT MONOCLONAL ANTIBODY (P42-23) 1 * 25 µl

Supplier: ENZO LIFE SCIENCES

PROTEASOME 19S RPT4/S10B SUBUNIT MONOCLONAL ANTIBODY (P42-23) 1 * 25 µl

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L-NIL dihydrochloride ≥97%

Supplier: ENZO LIFE SCIENCES

NOS inhibitor

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NS-2028 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

A potent and selective, cell-permeable inhibitor of nitric oxide (NO)-sensitive soluble guanylyl cyclase (sGC). Inhibition is irreversible. Inhibits also the basal, the YC-1 and the coenhanced sGC activity. Complete inhibition of NO-induced relaxation in vascular and nonvascular smooth muscle at 1μM.

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Chlorpromazine hydrochloride ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Antipsychotic working on a variety of receptors in the CNS

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NPC-15437 dihydrochloride ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

PKC inhibitor

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Tyrphostin AG 527 ≥98% (by HPLC)

Tyrphostin AG 527 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Tyrphostin AG 527 ≥98% (by HPLC)

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4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Potent inhibitor of histone deacetylases (HDACs) (IC50≤1µM).

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Daphnetin ≥97%

Supplier: ENZO LIFE SCIENCES

Protein kinase inhibitor

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Curcumin (from Curcuma longa) ≥98% (by HPLC), high purity

Supplier: ENZO LIFE SCIENCES

Curcumin (from Curcuma longa) ≥98% (by HPLC), high purity

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Catharanthine tartrate (from Catharanthus roseus) ≥90% (dry basis)

Supplier: ENZO LIFE SCIENCES

Starting material for the synthesis of the antitumor drugs vinblastine and vincristine. It is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.

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D-myo-Inositol-1,4,5-trisphosphate, hexapotassium salt ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Product of phosphatidylinositol phospholipid hydrolysis.

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Salubrinal ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Salubrinal ≥98% (by HPLC)

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