12716 Results for: "COLLECTION+PREFIX+HPLC"

PARP-2 specific inhibitor with 60-fold selectivity for PARP-2 (IC50=0.15 ± 0.04μM) over PARP-1 (IC50=9.0 ± 0.7μM). Can be used for further characterization of PARP-2 in pathophysiological conditions.

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Nutlin-3 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Inhibitor of p53/MDM2 interaction

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8-Hydroxyguanosine ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Oxidised form of the nucleoside guanosine.

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Puerarin ≥98% (by HPLC)

Supplier: Enzo Life Sciences

5-HT2c inhibitor

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A cell permeable, selective, and ATP-competitive inhibitor of Rho kinase (ROCK) activity (IC50=25µM). Does not inhibit the activation of Rho nor does it affect the in vitro activities of MLCK, PKCα, and SAPK2a/p38α. Shown to be less potent than Y-27632.

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Pioglitazone ≥97% (by HPLC)

Supplier: Enzo Life Sciences

PPARgamma activator.

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Aconitine ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Na⁺ channel activator.

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Wogonin ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Anti-inflammatory and antioxidant.

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SANT-1 ≥99% (by HPLC)

Supplier: Enzo Life Sciences

Potent, cell-permeable antagonist of the Shh signaling pathway.

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Arcyriaflavin A ≥95% (by HPLC)

Supplier: Enzo Life Sciences

Potent inhibitor of CDK4 / cyclin D1 (IC50 = 59nM). Inhibits human cytomegalovirus (HCMV) replication in cell culture (IC50 = 200nM).

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Compound E ≥98% (by HPLC)

Supplier: Enzo Life Sciences

gamma-Secretase inhibitor

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IC87114 ≥99% (by HPLC)

Supplier: Enzo Life Sciences

Cell permeable, selective inhibitor of PI 3-Kδ.

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AdipoRon ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Novel and orally active adiponectin receptor agonist for AdipoR1 and AdipoR2.

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NBQX ≥99% (by HPLC)

Supplier: Enzo Life Sciences

Most potent and selective AMPA/kainate receptor antagonist. More soluble form is NBQX disodium salt.

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Cabozantinib ≥99% (by HPLC)

Supplier: Enzo Life Sciences

Potent inhibitor of VEGFR-2, MET, Kit and FLT3-ITD

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Fenofibrate ≥98% (by HPLC)

Supplier: Enzo Life Sciences

PPARα activator.

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[6]-Gingerol ≥97% (by HPLC)

Supplier: Enzo Life Sciences

ATPase activator.

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Trichostatin A ≥99% (by HPLC)

Supplier: Enzo Life Sciences

HDAC inhibitor

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PI103 ≥97% (by HPLC)

Supplier: Enzo Life Sciences

Potent, cell permeable and ATP-competitive inhibitor of DNA-PK, phosphoinositide 3-kinase (PI(3)K), the rapamycin-sensitive (mTORC1) and rapamycin-insensitive (mTORC2) complexes of the protein kinase mTOR. Exhibits little activity towards a panel of more than 40 other kinases even at concentrations as high as 10µM. Effectively blocks cell proliferation in glioma cell lines both in vitro and in vivo.

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Thapsigargin ≥99% (by HPLC)

Supplier: Enzo Life Sciences

ATPase inhibitor

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Harpagoside ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Anti-inflammatory and anti-diabetic.

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Apstatin ≥95% (by HPLC)

Supplier: Enzo Life Sciences

Apstatin is a potent and selective inhibitor of aminopeptidase P (APP), Ki=2.6 µM for purified rat lung membrane-bound APP. It blocks the APP-mediated degradation of bradykinin. Limits myocardial infarct size alone or with ACE inhibitors.