19891 Results for: "5-Hydroksymetylo-2-furaldehyd&pageNo=11"

Supplier: ProSci Inc.

HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.

Supplier: Portwest

PW3 Hi-Vis baffle features HiVisTex Pro reflective tape for greater freedom of movement. The polyester ripstop outer combined with lightweight Insulatex thermal insulation offers an ultrasoft, water resistant solution for outdoor wear. Clever features include Ezee zip fastening and zipped pockets for secure storage.

Supplier: TOSOH Bioscience

These columns are designed for GFC of water soluble organic polymers, polysaccharides, oligosaccharides, DNA and RNA. They are based on a hydrophilic polymethacrylate matrix, which is stable from pH 2 to 12 and in aqueous eluents with up to 50% polar organic solvent.

Supplier: Cole Parmer

The 'hot' warning light will flash whenever the plate temperature is above 50 °C and will operate even when the hotplate is turned off if the unit is still connected to the mains. Powerful magnets and motor give stirring speed up to 1500 min⁻¹ and volumes up to 15 L. Model SB302 has a robust aluminium/silicon alloy top plate that will withstand the knocks of everyday use, the 600 W element and good heat transmission of this material gives rapid heating and ensures even temperature distribution across the whole of the plate. Model CB302 has an easy to clean glass ceramic top with excellent chemical and temperature resistance, which allows very high plate temperatures while ensuring the edges stay cooler, reducing the chance of accidental burns. With fitting for retort rod.

Supplier: VWR Collection

Do przygotowywania buforów, pożywek do hodowli komórkowych, podłoży mikrobiologicznych i innych płynów biologicznych. Są one wyposażone w wysokowydajne membrany PES firmy o dużej średnicy będące gwarancją właściwego działania i maksymalnej przepustowości. Pełny zestaw zawiera jednostkę filtrującą i butle odbieralnikową o ergonomicznym kształcie, z uformowanymi uchwytami na palce i opatentowaną nakrętką. System probówek wirówkowych i lejków umożliwia użytkownikowi filtrowanie płynów bezpośrednio do probówki o pojemności 15 lub 50 ml.

Supplier: VWR Collection

Agilent OpenLab CDS is the next generation chromatography data system, designed for ease of use and productivity. OpenLab CDS offers the most comprehensive instrument control and data acquisition for Hitachi HPLC and amino acid analysers. In addition, it supports an expanded array of instrumentation from other vendors, for example Agilent LC, GC and LC/MS. Whether you like to control a single instrument or a huge network of different analytical instruments, OpenLab CDS grows with your needs.

Supplier: VWR Collection

Stainless steel circulating baths with choice of Advanced Programmable or Advanced Digital temperature controller. Both are easy to navigate with large, intuitive displays and multiple communication options, including USB-A and B, RS232/485, Ethernet and external temperature probe. The reservoir drain can be accessed by removing the front panel. All models feature user-adjustable, high temperature safety cut-off points, as well as over-temperature protection. The surface is cool to the touch, even when operating at high temperatures.

Supplier: EPPENDORF

For any application that requires sample/reaction mixing and heating the Eppendorf® ThermoMixer F family is what you need. Whether you work with 0,5/1,5/2,0 ml tubes or plates (MTP and DWP) the dedicated fixed blocks offer a perfect solution for your special application.

Supplier: IKA

Powerful laboratory stirrers for quantities up to 40 or 100 litres (H₂O). Units automatically adjust the speed through microprocessor-controlled technology within the speed range of 0/30 to 2000 min⁻¹ (EUROSTAR 60 models) or 0/30 to 1300 min⁻¹ (EUROSTAR 100 models). Safety circuits ensure automatic cut-off in anti-stall or overload conditions. The actual shaft and pre-set speed are constantly monitored, and variations adjusted automatically. This guarantees a constant speed even with changes in sample viscosities.

Supplier: Merck

TLC plates, unmodified silica gel 60
Merck silica gel 60 has a unique polymeric binder that results in a uniform, hard surface that will not easily crack or blister. This smooth, extremely dense plate coating ensures narrow bands and maximum separation efficiency with the lowest background noise. Layer thickness 250 μm and particle size of 10 to 12 µm. Two inorganic fluorescent indicators for UV detection of colourless substances.

Supplier: HUBER

Unichillers offer better efficiency, stable pressure and delivery performance with a constant cooling water temperature compared to traditional tap water cooling. Chillers also reduce water consumption and help conserve the environment whilst lowering operating costs.

Supplier: TOSOH Bioscience

SkillPak 1 and 5 ml columns are designed for fast method development, resin screening or sample concentration. Pre-packed with TOYOPEARL®, TSKgel® or Ca++Pure-HA™ process chromatography media, these columns offer superior separation of biomelocules, such as monoclonal antibodies, proteins and oligonucleotides. SkillPak 50 and 200 ml pre-packed columns are the best solution for seamless scale up of methods developed on SkillPak 1 and 5.

Supplier: Portwest

Classically styled, gives enhanced protection whatever the elements. With a mobile phone pocket and a radio loop as standard, this jacket is warm, comfortable and water repellent.

Supplier: Portwest

Be seen and be comfortable in this excellent quality jacket. The unique lightweight material offers an unrivaled combination of breathability, waterproof, and windproof protection.

Supplier: Portwest

This jacket is made from 300D Oxford Weave fabric (300 denier polyester yarn) which features a high abrasion and tear resistance. The PU coating on the inside makes the fabric durable and waterproof, while the outer has a water- and stain-repellant coating which helps keep the garment clean.

Supplier: LABCONCO

Protector premier hoods are suitable for general chemistry applications and also explosion-proof models are available for laboratories with potentially explosive/flammable atmospheres. Hoods are available with a built-in standard fiberglass blower, or an explosion-proof fiberglass blower, or without a blower (remote blower sold separately).

Supplier: Air Liquide

These vessels are designed for long term storage of biological samples in straws, cryo-vials and bags. A variety of electronic options on all models rack or canister storage systems for the samples.
Made of aluminum and composite materials.

Supplier: EPPENDORF

Eppendorf Deepwell plates 96-well, 500 µl offer efficient sample handling with features like OptiTrack® matrix for rapid identification and g-Safe® technology for stability during centrifugation. SafeCode variants provide secure three-level coding, including error correction for reliable identification, ensuring flexibility and accuracy in experimental workflows.

Supplier: HICHROM

[EN]COLUMN GC SS CUSTOM PACKED 1 * 1 SZT

Supplier: IKA

The RCT basic magnetic stirrer provides reliability, an exceptionally long product lifetime and the highest safety standards. RCT basic is suitable for stirring tasks up to 20 L (H₂O) and reaches temperatures up to 310 °C. With the connection option for an external temperature sensor (PT1000.60), the temperature can be measured and controlled directly in the reaction medium. Thanks to insulation of the aluminium heating plate, maintenance-free EC motor and electronic switching power supply, RCT basic features excellent energy efficiency as well as reduced self-heating of the heating plate during stirring operation, contributing to a more sustainable laboratory.

Supplier: EPPENDORF

Eppendorf epT.I.P.S.® Box 2.0, available with 'Eppendorf Quality' pipette tips or as an empty box, improves lab efficiency with innovative TwinLid® technology, enhanced stackability, and superior ergonomics for safe and organised pipetting.

Supplier: VACUUBRAND

The PC 3001 VARIO select pumping unit precisely controls the vacuum level in order to achieve unparalleled process control. The integrated VACUU·SELECT controller provides an easy-to-use, application based interface that covers all common lab applications.

Supplier: ProSci Inc.

CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP11A1 localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.

Supplier: Portwest

These hi-vis workwear ranges are made from a premium durable polyester/cotton. These fabrics offer variations in weight and composition. The bright fluorescent capabilities of fabrics combined with the garments retro reflective stripes offers the highest possible visibility in poor light or adverse weather conditions.

Supplier: BUCHI

The Rotavapor R-250 EX is the EX rated version of the Rotavapor R-250. It fulfills the high requirements of the ATEX regulations and fits perfect to your Ex-proof production laboratory. It is designed for easy and safe operation combined with high performance.

Supplier: Thermo Fisher Scientific

These devices can be used for a wide range of applications including low molecular-weight contaminant removal, buffer exchange, desalting, equilibrium dialysis, and concentration. The cassette membrane is composed of low-binding regenerated cellulose and features a hermetically sealed sample chamber to maintain the highest possible sample retention. This type of membrane is compatible with a number of common chemicals and buffers. The colour-coded transparent frames of the Slide-A-Lyzer® cassette allow instant recognition of the MWCO of the membrane and make viewing the needle easier during sample injection.

Supplier: FRISTADS KANSAS

Sustainable high-vis stretch trousers ideal for service and logistics. Full 4-way stretch with rib-knit stretch panels at the waist for double the comfort. Made of bio-based and recycled materials and reinforced in exposed areas.

Supplier: Portwest

These fully waterproof anti-static bomber jackets provide multi-norm protection in hazardous conditions. These are designed with chemical resistance and a detachable hood.

Supplier: Portwest

The DX4 Baffle Gilet uses a body-mapped design to balance insulation and freedom of movement. Hard-wearing nylon front and back panels are padded with Insulatex to keep the core body area warm. Two zipped chest pockets, side entry pockets, and internal pockets offer plenty of secure storage space.

Supplier: ProSci Inc.

SPG11 Antibody: Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders.  Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia (cHSP) in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration. Mutations of the SPG11 gene encoding the spatacsin protein have been identified as a major cause of HSP-TCC. Spatacsin is a potential transmembrane protein that is phosphorylated upon DNA damage. It is expressed in all structures of the brain, with a high expression in the cerebellum. SPG11 mutations may occur more frequently in familial than sporadic forms of cHSP without TCC. Kjellin syndrome is found to be associated with mutations in not only the SPG15 gene but also SPG11 gene.  Recent studies show Parkinsonism may initiate SPG11-linked HSP TCC and that SPG11 may cause juvenile Parkinsonism.