123355 Results for: "\u0141ódeczki+do+spala\u0144&pageNo=14"

Supplier: Apollo Scientific

6,7-Dihydro-5H-[1,3]dioxolo[4,5-f]isoindole hydrochloride 95%

Supplier: Trajan Scientific and Medical

Needle, syringe, Diamond MS, Ultra smooth hydrophobic treated, Gauge: 23, Length: 57 mm, Ø ext.: 0,63 mm, Ø int.: 0,11 mm, Type of tip: Cone, Red

Supplier: Thermo Fisher Scientific

(2R,5R)-1-[2-(1,3-Dioxolan-2-yl)phenyl]-2,5-dimethylphospholane 97%

Supplier: Abcam

Rabbit monoclonal [EPR25299-11] to HIRA/HIR - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR17989-134] to OB Cadherin - BSA and Azide free (Capture).

Supplier: Abcam

Rabbit monoclonal [EPR23155-12] to OX40L/TNFSF4 - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR18982-13] to n-Myc/MYCN - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR27119-17] to SLC26A2/DTD - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR20369-15] to Tissue Factor - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [BL-149-2H5] to Brd4 - BSA free.

Supplier: Abcam

Rabbit monoclonal [EPR27116-147] to SEMA4C/SEMAI - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR19954-188] to IL-18 - BSA and Azide free (Capture).

Supplier: US Biological

Anti-MAP Kinase 15 Rabbit Polyclonal Antibody (FITC (Fluorescein))

Supplier: Bioss

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Supplier: Bioss

Calpains are a family of cytosolic calcium activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin and cytoskeletal interactions, and synaptic plasticity. Calpain 12 was first described in the mouse, most strongly in the skin, and maps to mouse chromosome 7. Isoforms differ in the carboxyterminal ends, ending with aberrant domain III and lacking domain IV. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV, making Calpain 12 most similar to calpains 1 and 2.

Supplier: Bioss

Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain. Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer.

Supplier: Bioss

Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain. Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer.

Supplier: Bioss

The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecules. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-10 is a 228 amino acid multi-pass membrane protein that belongs to the claudin family and plays an important role in cell-adhesion activity and tight junction-specific events.

Supplier: Bioss

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.

Supplier: Bioss

Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

Supplier: Bioss

Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodelling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.

Supplier: ProSci Inc.

Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.

Supplier: Bioss

Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XI, also known as SYT11 (Synaptotagmin-11), is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung. Like other Synaptotagmin proteins, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking. Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinson's disease gene product), the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex. Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, including schizophrenia and Parkinson's disease.

Supplier: Bioss

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyses the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Supplier: Bioss

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Supplier: Apollo Scientific

2-(2-Aminopropan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

Supplier: Apollo Scientific

1,6-Anhydro-2,3,4-tri-O-benzyl-beta-D-glucopyranose 98% min

Supplier: Apollo Scientific

Photoreactive -Primary amine reactive -Fluorescent label

Supplier: Apollo Scientific

1,3-Dimethyl-1H-pyrazole-5-boronic acid pinacol ester 97%

Supplier: Biotium

Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.