123352 Results for: "\u0141ódeczki+do+spala\u0144&pageNo=14"

Supplier: ProSci Inc.

Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.

Supplier: Bioss

Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XI, also known as SYT11 (Synaptotagmin-11), is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung. Like other Synaptotagmin proteins, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking. Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinson's disease gene product), the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex. Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, including schizophrenia and Parkinson's disease.

Supplier: Bioss

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyses the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Supplier: Bioss

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Supplier: Apollo Scientific

2-(2-Aminopropan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

Supplier: Apollo Scientific

1,6-Anhydro-2,3,4-tri-O-benzyl-beta-D-glucopyranose 98% min

Supplier: Apollo Scientific

Photoreactive -Primary amine reactive -Fluorescent label

Supplier: Apollo Scientific

1,3-Dimethyl-1H-pyrazole-5-boronic acid pinacol ester 97%

Supplier: Biotium

Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Supplier: Biotium

Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Supplier: Biotium

Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

Supplier: Biotium

This antibody recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha fetoprotein (AFP). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. The yolk sac and the liver produce AFP during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spinal bifida and anencephaly.

Supplier: Biotium

Recognizes a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

Supplier: Apollo Scientific

1-(2-Methoxy-phenyl)-n1,n1-dimethyl-ethane-1,2-diamine 98%

Supplier: Apollo Scientific

Methyl (4s)-trans-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate 95%

Supplier: Apollo Scientific

1-(2,3-Difluorophenyl)-N-[(1,5-dimethyl-1H-pyrazol-4-yl)methyl]methanamine

Supplier: Apollo Scientific

9-Bromo-7-methyl-2-morpholino-4H-pyrido[1,2-a]pyrimidin-4-one ≥98%

Supplier: Apollo Scientific

4-(3,4-Dihydro-2H-1,5-benzodioxepin-7-yl)benzenecarboxylic acid 95%

Supplier: Abcam

Rat monoclonal [JES5-2A5] to IL-10.

Supplier: Abcam

Rabbit monoclonal [EPR23959-18] to GRP78 BiP - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR19779-124] to IL-1 beta - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR19942-285] to IL-15 - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR22249-81] to IL-18 - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR25917-13] to TNF beta - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR27864-16] to Methyltransferase like 5 - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [UDD3 30(12)] to LRRK2.

Supplier: Abcam

Rabbit monoclonal [EPR27291-17] to Integrin alpha 1 - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EP1615Y] to Cytokeratin 16/K16.

Supplier: Biotium

Recognizes a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

Supplier: Abcam

Rabbit monoclonal [KRT10/1990R] to Cytokeratin 10 - BSA and Azide free.