FFN511 ≥98% Fluorescent substrate for VMAT2

First novel fluorescent false neurotransmitter. Enables optical imaging of presynaptic terminal activity. Inhibits 5-HT binding to VMAT2 (IC₅₀ = 1 μM (comparable to dopamine itself)). Released via exocytosis in the striatum in mouse acute slice preparation. Labels dopamine and other presynaptic terminals in the striatum. Compatible with GFP tags and other optical probes. Sufficiently bright, photostable and suitable for two-photon fluorescence microscopy. View the technique online For highly selective labelling of dopaminergic presynaptic termainals FFN102 is recommended.

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