Agilent Technologies extended light path capillaries ('bubble' cell capillaries) can be used to improve sensitivity 3- to 5-fold over standard capillaries. With extended light path capillaries, the inner diameter is increased only at the detection window, offering the sensitivity of a wide inner diameter capillary and the low current generation of a narrow one.

Resolution is not sacrificed when used with matching optical alignment interfaces from Agilent.

Through a computer-controlled proprietary process, the diameter is increased three to five times, with a manufacturing precision better than 3%. This process allows an extension of the detection pathlength of 25 μm Int.Ø capillaries to 125 μm, 50 μm to 150 μm, 75 μm to 200 μm.