Specifications
- Antibody type:Primary
- Antigen name:IDH3B
- Clonality:Polyclonal
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Epitope:151-250/385
- Form:Liquid
- Antigen synonyms:Isocitric dehydrogenase|NAD+-specic isocitrate dehydrogenase b subunit|isocitrate dehydrogenase 3, beta subunit|NAD+-specic ICDH|FLJ11043|OTTHUMP00000030023_ OTTHUMP00000030024|IDH3B|H-IDHB|RP46|MGC903|mitochondrial|Isocitrate dehydrogenase [NAD] subunit beta|IDH3B_HUMAN|Isocitric dehydrogenase subunit beta|Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial|NAD+-specic ICDH subunit beta|NAD+-specic isocitrate dehydrogenase beta
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:39 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human IDH3B
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Isocitrate dehydrogenases catalyse the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilises NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localise to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyse the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Type: Primary
Antigen: IDH3B
Clonality: Polyclonal
Clone:
Conjugation: FITC
Public Immunogen Range: 151-250/385
Host: Rabbit
Isotype: IgG
Reactivity: