Specifications

• Koniugacja:
  Unconjugated
• Rodzaj białka / peptydu:
  Rekombinowany
• Źródło:
  HEK293 cells
• Gatunki:
  Human
• Sekwencja znaczników:
  His Tag
• Warunki przechowywania:
  –20 °C
• Zawartość endotoksyn:
  Less than 1,0 EU per μg by the LAL method
• Aktywność biologiczna:
  Measured by its binding ability in a functional ELISA. Immobilised Human Siglec-15, His Tag (Cat. No. SG5-H52H3) at 5 μg/ml (100 μl/well) can bind Mouse Human chimeric MAb (5G12, Human IgG1) with a linear range of 0,3 - 2 ng/ml (QC tested). Measured by its binding ability in a functional ELISA. Immobilised Human Siglec-15, His Tag (Cat. No. SG5-H52H3) at 10 μg/ml (100 μl/well) on Nickel Coated plate, can bind Neu5Ac(a2-6)GalNAc-PAA-biotin with a linear range of 0.078-5 μg/ml (Routinely tested). Loaded Mouse Human chimeric MAb (5G12, Human IgG1) on AHC Biosensor, can bind Human Siglec-15, His Tag (Cat. No. SG5-H52H3) with an affinity constant of 0,52 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
• Identyfikator genu:
  Q6ZMC9-1
• Synonimy białek:
  Siglec-15|SIGLEC-15|Siglec15|CD33L3|CD33 antigen-like 3|sialic acid-binding Ig-like lectin 15
• Nazwa białka / peptydu:
  Siglec-15
• Czystość:
  >90% as determined by SDS-PAGE.
• Waga molekularna:
  28,4 kDa
• Poziom endotoksyn:
  Low
• Formulacja:
  Lyophilised from 0,22 μm filtered solution in 25 mM MES, 150 mM NaCl, pH 5,5. Normally trehalose is added as protectant before lyophilisation.
• Temperatura transportu:
  RT