Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine that is constitutively produced by thymus tissue and activated peripheral blood mononuclear cells (PBMCs), including dendritic cells. TARC signals through the CCR4 receptor to induce chemotaxis of Type 2 T helper (Th2) cells. TARC is important in asthma and allergic diseases, along with bacterial and viral infections.
- High quality
- Low endotoxin
- Affordable
Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.
- Koniugacja:Unconjugated
- Funkcja białka:Cytokine
- Rodzaj białka / peptydu:Rekombinowany
- Źródło:E. coli
- Gatunki:Human
- Warunki przechowywania:−20 °C
- Zawartość endotoksyn:Endotoxin LAL (EU/µg) ≤0.1
- Aktywność biologiczna:Bioactivity assay: Inhibition of IL-4-induced HT-2 cell proliferation, ED50 ≤0,5 ng/ml, bioactivity ≥2,0×10⁶ units/mg
- Identyfikator genu:P01137
- Instrukcje dotyczące odtwarzania:Sterile 10 mM HCl at 0,1 mg/ml
- Nie zawiera endotoksyn:N
- Bez przewoźnika:Y
- Bez proteazy:N
- Wolne od zwierząt:N
- Synonimy białek:cartilage-inducing factor|Differentiation inhibiting factor
- UniProtKB:P01137
- Nazwa białka / peptydu:TGF-beta1
- Czystość:≥95%
- Waga molekularna:12,8/25,6 kDa
- Sekwencja:ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
- Poziom endotoksyn:Low
- Formulacja:0,1% trifluoroacetic acid (TFA) and trehalose in a 20:1 trehalose to protein ratio
- Wolne od nukleaz:N
- Typ:RUO
- Temperatura transportu:RT
- Przetestowane aplikacje:Bioassay
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