CD8⁺ cytotoxic T cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures.

• Purity of >90% by flow cytometry
• Test negative for Hepatitis B, Hepatitis C, HIV 1/2, HTLV-I/II, HIV-1/HCV/HBV nucleic acid, WNV nucleic acid, Trypanasoma cruzi and Syphilis
• Cryopreserved in CryoStor® CS10 media

CD8⁺ cytotoxic T cells fulfill the role of regulating and/or carrying out the body’s immune response by eliminating intracellular pathogens such as viruses, and some bacteria and parasites. Upon recognition of an infected cell, the CD8⁺ T cell initiates apoptosis through the targeted release of effector proteins contained in granules within the T cell.

Storage: Either prepare cells for long term storage in liquid nitrogen vapor phase or thaw for use. Storage in liquid phase nitrogen is NOT recommended. Short term storage of cells (less than 2 weeks) at −80 °C is acceptable, but should be minimised to ensure maximum stability. Once thawed, samples must be used immediately.