Anti-CCL5 Mouse Monoclonal Antibody [clone: 5B3-D5]
Catalog # PRSIXP-5735-M
Supplier: ProSci Inc.
Specifications
- Antibody type:Primary
- Antigen name:Chemokine (C-C motif) ligand 5
- Antigen symbol:CCL5
- Clonality:Monoclonal
- Clone:5B3-D5
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- Isotype:IgG2b
- Reactivity:Human
- Western blot:Yes
- Neutralisation:Yes
- Form:Lyophilized
- Gene ID:6352
- Antigen synonyms:T-cell specific protein p288|normally T-expressed|C-C motif chemokine 5|t cell-specific protein P228|SIS-delta|small-inducible cytokine A5|small inducible cytokine subfamily A (Cys-Cys)|regulated upon activation|eoCP|and presumably secreted|beta-chemokine RANTES|T-cell-specific protein RANTES|member 5|eosinophil chemotactic cytokine|small inducible cytokine A5 (RANTES)
- Storage temperature:Stable at room temperature for at least one month and for greater than a year when kept at –20 °C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. Stable for at least six weeks at 2-4 °C when reconstituted.
- Shipping temperature:RT
- Immunogen:Monoclonal antibody against human RANTES designated as VL-1 was purified from ascites fluid on a Protein A affinity column.
- Size:500 µg
- Pk:500 µG
Specifications
About this item
RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV). It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.
Type: Primary
Antigen: CCL5
Clonality: Monoclonal
Clone: 5B3-D5
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human