Anti-NLRP4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
BOSSBS-6855R-A488
: Bioss
- Antibody type:Primary
- Antigen name:NLR Family, Pyrin Domain Containing 4
- Antigen symbol:NLRP4
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 488
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Cross adsorption:No
- Form:liquid
- Gene ID:147945
- Antigen synonyms:PYPAF4|NACHT|Leucine Rich Repeat And PYD Containing 4|PYRIN-Containing APAF1-Like Protein 4|PAAD And NACHT-Containing Protein 2|NALP4|RNH2|Cancer/Testis Antigen 58
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:370-420/994
- Purification:Purified by Protein A
- Pk:100 µl
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: NLRP4
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat