Anti-GRIN2B Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Catalog # BOSSBS-3306R-A488
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:Glutamate Ionotropic Receptor NMDA Type Subunit 2B
- Antigen symbol:GRIN2B
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 488
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Cross adsorption:No
- Form:liquid
- Gene ID:2904
- Antigen synonyms:hNR3|GluN2B|NR2B|EIEE27|MRD6|NMDAR2B|glutamate ionotropic receptor NMDA type subunit 2B
- Modification:phospho-Tyr1070
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:1040-1090/1484
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200
Type: Primary
Antigen: NMDAR2B
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat