The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO.
Type: Primary
Antigen: CD45
Clonality: Monoclonal
Clone: 2D1
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
- Catalog No:
- 35-9459-T025
- 35-9459-T100
- Antigen symbol:
- PTPRC
- PTPRC
- Antigen name:
- Protein tyrosine phosphatase receptor type C
- Protein tyrosine phosphatase receptor type C
- Antigen synonyms:
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- FITC (Fluorescein Isothiocyanate)
- FITC (Fluorescein Isothiocyanate)
- Clone:
- 2D1
- 2D1
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 5788
- 5788
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Flow cytometry:
- Yes
- Yes
- Cross adsorption:
- No
- No
- Storage temperature:
- Store undiluted at 2-8 °C, protect from light, do not freeze.
- Store undiluted at 2-8 °C, protect from light, do not freeze.