The 104 antibody reacts with mouse CD45.2, also known as Ly5.2, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
The 104 antibody is typically used as a leukocyte marker in Ly5.2 mouse strains C57BL/6, BALB/c, C58, DBA/1, DBA/2, C3H/He, CBA, 129, A and AKR. The antibody has been demonstrated to be specific for CD45.2 and is not cross-reactive with CD45.1-bearing cells.
Type: Primary
Antigen: CD45.2 (CD45.2)
Clonality: monoclonal
Clone: 104
Conjugation: APC (Allophycocyanin)/Cy7®
Epitope:
Host: Mouse
Isotype: IgG2a Kappa
Reactivity: Mouse
- Catalog No:
- 25-0454-U025
- 25-0454-U100
- Antigen symbol:
- PTPRC
- PTPRC
- Antigen name:
- Protein tyrosine phosphatase receptor type C
- Protein tyrosine phosphatase receptor type C
- Antigen synonyms:
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- APC (Allophycocyanin)/Cy7®
- APC (Allophycocyanin)/Cy7®
- Clone:
- 104
- 104
- Reactivity:
- Mouse
- Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- 19264
- 19264
- Isotype:
- IgG2a kappa
- IgG2a kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoPrecipitation:
- Yes
- Yes
- Flow cytometry:
- Yes
- Yes
- Neutralisation:
- Yes
- Yes
- Cross adsorption:
- none
- none
- Storage temperature:
- Store undiluted at 2...8 °C, protected from light
- Store undiluted at 2...8 °C, protect from light, do not freeze
- Shipping temperature:
- Ice
- Ice
- Tested applications:
- Flow Cytometry
- Immunofluorescence microscopy
: VWR Chemicals
: VWR Collection
: KIMBERLY CLARK
: VWR Chemicals
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection