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3 results for Leptomycin B

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Leptomycin B

Supplier: Apollo Scientific

Potent inhibitor of nuclear export.

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Leptomycin B 0.2 mg/ml ≥98% (by HPLC)

Supplier: Enzo Life Sciences

A potent and specific nuclear export inhibitor. In addition to antifungal and antibacterial activities, blocks the cell cycle and is a potent anti-tumor agent.

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Leptomycin B

Supplier: Abcam

Potent inhibitor of CRM-1-mediated (exportin-1) nuclear export. Displays antibiotic, antifungal, and antitumor properties and blocks the cell cycle at G₁ and G₂ phases. Potent inhibitor of nucleo-cytoplasmic translocation of Rev. Also shown to suppress HIV-1 replication in human monocytes (IC₅₀ = 600 pM).

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