Anti-INIP Rabbit Polyclonal Antibody

Catalog # BOSSBS-9491R

Supplier: Bioss

Catalog # BOSSBS-9491R

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
INTS3 And NABP Interacting Protein
Antigen symbol:
INIP
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Environmentally Preferable:
Form:
liquid
Antigen synonyms:
SOSSC_HUMAN|Chromosome 9 open reading frame 80|Sensor of ssDNA subunit C|Ssbip1|hSSBIP1|SSB-interacting protein 1|SOSS complex subunit C|C9orf80.|SOSS C|MISE|SOSSC|Single-stranded DNA-binding protein-interacting protein 1|RP11-276E15.2|Sensor of single-strand DNA complex subunit C|SOSS-C
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
Concentration:
1 ug/ul
Shipping temperature:
4 °C
Purification:
Purified by Protein A.
Size:
100 μg
Pk:
100 µl

Specifications

About this item

The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Type: Primary
Antigen: INIP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat