Management of change

Robust programs and tools to minimize risk

Our Management of Change (MOC) and change notification programs help you stay in control of changing situations, minimizing risks to your production processes.

How Avantor's programs work

  • Conditions that may be subject to change are proactively identified by Avantor's quality and regulatory teams.
  • Associated risks are evaluated and key staff in your organization are notified, per the applicable change notification procedure

We currently have three programs tied to our specific brands:

  1. Management of Change (MOC) for J.T.Baker® and Macron Fine Chemicals™ brand products
  2. Change Notification Service (CNS) for products purchased through VWR
  3. Change Notification for NuSil brand products

Avantor Management of Change Program:

The Avantor MOC program puts key information into your hands for J.T.Baker® and Macron Fine Chemicals™ brand products so you can stay in control of changing situations and minimize risks associated with changes to manufacturing processes.

These products are classified under change control tiers to ensure you always get the MOC notification you need for each specific product. You will receive Change Notification communications from Avantor via your registered email if you have either enrolled in our Management of Change (MOC) program or have directly purchased an affected product within the past three years.

MOC Category HR
Highly Regulated
Regulated Limited
Non-Regulated, With Information
Bulk Pharmaceutical Yes Yes Yes No No
Intended/Potential Use API, BPE BPE Processing Aids, Food, Nutraceuticals, Cosmetics Reagents Reagents
Grades USP, NF, EP, BP, JP, ChP USP, NF, EP, BP, JP, ChP IP, EP, FCC ACS, Reagents ACS, Reagents
Notification of Change Yes, Level 2 Yes, Level 2 Yes, Level 2 Limited if registered in MOC database None
Industry Reference IPEC, Q7 IPEC, Q7 FCC, IP, EU None None
Regulating Body FDA, cGMP FDA, cGMP IFDA, EU, Food GMP None None

VWR, Part of Avantor, Change Notification Service (CNS):

Change notification for products purchased through VWR is available by registration through the VWR CNS program, which provides complete, consistent, reliable and transparent access to change notification for these materials. A secure web platform allows customers to see new change notices, as well as a history of past changes.

NuSil’s Change Notification

For more information on NuSil’s Change Notification policy please contact us at [email protected]

Avantor® is a leading global provider of mission-critical products and services to customers in the life sciences and advanced technologies & applied materials industries. The company operates in more than 30 countries and delivers an extensive portfolio of products and services. As our channel brand, VWR offers an integrated, seamless purchasing experience that is optimized for the way our customers do business. We set science in motion to create a better world. For information visit, and find us on Linkedin, Twitter and Facebook.