1424 Results for: "TMC HALLCREST"

Supplier: ENZO LIFE SCIENCES

Putative endogenous member of a growing family of lipo-amino acids (N-acyl amino acids).

Supplier: ENZO LIFE SCIENCES

Tyrosine kinase inhibitor. It has been shown to block TNFα induced cytotoxicity and to block glucocorticoid-induced COX-2 activity in human amnion cells (IC50=21μM). It is also reported to inhibit guanylyl cyclase.

Supplier: ENZO LIFE SCIENCES

Pyruvate kinase M2 activator.

Supplier: ENZO LIFE SCIENCES

Cannabinoid receptor ligand.

Supplier: ENZO LIFE SCIENCES

The non-protein amino acid L-canavanine is an analog of L-arginine. Selective inducible nitric oxide synthase (iNOS; NOS II) inhibitor. Induces apoptotic cell death and shows antiproliferative and immunotoxic effects.

Supplier: ENZO LIFE SCIENCES

Inhibitor of dopamine and norepinephrine transporters

Supplier: ENZO LIFE SCIENCES

Inhibits the metalloprotease neprilysin (neutral endopeptidase 24.11) and neprilysin 2. Inhibits opioid-degrading enzymes, potentiating THC-induced antinociception. Potentiates the effects of natriuretic peptides. Blocks enzymatic degradation of luteinizing hormone releasing hormone (LHRH).

Supplier: ENZO LIFE SCIENCES

Specific non-chelating small-molecule inhibitor of MMP-12 (IC50 = 14 nM). At higher concentrations it inhibits other MMPs, but spares MMP-1, making it a valuable tool for investigation of MMP activity and function.

Supplier: ENZO LIFE SCIENCES

DPPIV/DPP4 inhibitor

Supplier: Abcam

TMB substrate recommended for use with the Matched Antibody Pair kits for sandwich ELISA.

Supplier: AAT BIOQUEST

Z-DEVD-AMC is a fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

Supplier: AAT BIOQUEST

Coronaviruses (CoVs) can infect humans and multiple species of animals, causing a wide spectrum of diseases.

Supplier: AAT BIOQUEST

Pro-AMC is a sensitive fluorogenic protease substrate.

Supplier: ENZO LIFE SCIENCES

Inhibits yeast growth and activates ceramide-activated protein phosphatase (CAPP).

Supplier: ENZO LIFE SCIENCES

Activates TRPV1. Endogenous anandamide-like lipid which regulates appetite but does not bind to cannabinoid receptors. In rats, food intake is inhibited by oral oleylethanolamide. Induces satiety by activation of PPARα. Inhibits ceramidase.

Supplier: ENZO LIFE SCIENCES

Necroptosis inhibitor

Supplier: ENZO LIFE SCIENCES

PKC activator.

Supplier: ENZO LIFE SCIENCES

Sphingosine kinase inhibitor

Supplier: ENZO LIFE SCIENCES

TRPV1 antagonist

Supplier: ENZO LIFE SCIENCES

CaM kinase kinase inhibitor

Supplier: ENZO LIFE SCIENCES

Competitive, mechanism-based inhibitor of matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9). It possesses Ki values in the nanomolar range against the gelatinases (14nM for MMP-2; 600nM for MMP-9), but in the micromolar range against other metalloproteinases (206µM for MMP-1, 15µM for MMP-3, 96µM for MMP-7, and 4µM for ADAM17/TACE). This inhibitor has also been used in vitro, in vivo, and in tissue culture. In vivo, it is metabolized to an even more potent gelatinase inhibitor.

Supplier: ENZO LIFE SCIENCES

BIBB 515 is a potent and selective inhibitor of 2,3-oxidosqualene cyclase (OSC) in vivo. BIBB 515 inhibits LDL production in both normolipemic and hyperlipemic hamsters and may represent a novel approach for the development of lipid lowering drugs.

Supplier: ENZO LIFE SCIENCES

Potent, selective and irreversible inhibitor of MAG lipase (IC50=8nM vs 4µM for FAAH). JZL-184-treated mice displayed a number of CB1-dependent behavioral effects including analgesia, hypothermia and hypomotility as well as increased levels of 2-arachidonoylglycerol in the brain ( approx. 8-fold, with no effect on anandamide levels). JZL-184 produces a rapid and sustained blockade of brain 2-AG hydrolase activity in mice. It blocks neuropathic pain and enhances retrograde endocannabinoid signaling.

Supplier: ENZO LIFE SCIENCES

Active metabolite of sulindac. Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling.

Supplier: ENZO LIFE SCIENCES

Adenylate cyclase inhibitor

Supplier: ENZO LIFE SCIENCES

Anandamide transport inhibitor

Supplier: ENZO LIFE SCIENCES

Cannabinoid receptor ligand.

Supplier: ENZO LIFE SCIENCES

Benzodiazepine receptor ligand.

Supplier: ENZO LIFE SCIENCES

EGFR inhibitor

Supplier: ENZO LIFE SCIENCES

Ikarugamycin inhibits the uptake of oxidized low-density lipoprotein in mouse macrophages. It blocks PMA and Nef-mediated cell surface CD4 down-regulation. Ikarugamycin is emerging as a general inhibitor of clathrin-coated pit-mediated endocytosis and appears to be a useful agent for studying the process of endocytosis.