1424 Results for: "TMC HALLCREST"
5-Iodotubercidin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits ERK2 (Ki = 525nM). Also inhibits adenosine kinase (Ki = 30nM), CK1 and CK2 and insulin receptor kinase (IC50 ranging from 0.4-28µM).
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Misoprostol ≥99% (by TLC)
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Prostanoid receptor ligand.
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AACOCF3 ≥98% (by TLC)
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AACOCF3 is a trifluoromethylketone derivative of arachidonic acid. It is a selective inhibitor of human cytosolic PLA2 and Ca2+-independent PLA2 (iPLA2, IC50=15 µM). It is active in intact platelets and U937 cells (IC50=8 µM). It also inhibits fatty acid amide hydrolase (100% at 7.5 µM).
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Manoalide ≥98% (by TLC)
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Phospholipase inhibitor
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Simvastatin ≥98% (by TLC)
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HMG-CoA reductase inhibitor
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HBDDE ≥95% (by TLC)
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Inhibits PKCα (IC50=43 µM) and PKCγ (IC50=50 µM) without inhibiting the δ, βI and βII isotypes.
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H-Arg-AMC·2HCl
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Substrate for cathepsin H and aminopeptidases
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α-Hydroxytriazolam ≥96% (by TLC)
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An active but short-lived metabolite of triazolam.
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Isotetrandrine ≥98% (by TLC)
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Phospholipase inhibitor
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Alamethicin ≥98% (by TLC)
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Mixture of alamethicin homologs. Membrane permeabilizing antibiotic. Applications include increasing [32P] incorporation into phosphatidylinositol 4-phosphate and permeabilization of sarcoplasmic reticulum vesicles. Causes fusion of lipid vesicles.
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Lovastatin ≥98% (by TLC)
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HMG-CoA reductase inhibitor
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Dexamethasone ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
Glucocorticoid receptor ligand
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H-7 dihydrochloride ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits PKA (Ki=3.0μM), PKG (Ki=5.8μM), MLCK (Ki=97μM) and PKC (Ki=6μM). Also inhibits myosin light chain kinase. Induces apoptotic DNA fragmentation and cell death. Inhibits telomerase activity in treated NPC-076 cells. Cell permeable.
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SB216763 ≥98% (by TLC)
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Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model.
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DMNQ ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inducer of intracellular ROS generation.
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α-Hydroxyalprazolam ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Metabolite of alprazolam.