"Stemcell Technologies"

Supplier: Stemcell Technologies

Ideal for the permeabilisation of fixed cells during labeling of cytokines and other cytoplasmic antigens. Intracellular Permeabilisation Buffer (10X) is uniquely formulated for optimal resolution and to reduce background and is suitable for use with fluorochrome-conjugated antibodies for flow cytometry.

Supplier: Stemcell Technologies

Rat monoclonal antibody against mouse CD8a, APC-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD83, FITC-conjugated.

Supplier: Stemcell Technologies

Stem cell factor (SCF) is an early-acting cytokine that plays a pivotal role in the regulation of embryonic and adult hematopoiesis. SCF promotes cell survival, proliferation, differentiation, adhesion, and functional activation of cells at multiple levels of the hematopoietic hierarchy. Together with other cytokines such as thrombopoietin and Flt3/Flk-2 Ligand, SCF is commonly used to promote expansion of primitive hematopoietic stem cells and multi-potent progenitor cells in culture (Huang et al.; Kent et al.). In synergy with various growth factors, including IL-2, IL-3, IL-6, IL-7, G-CSF, and erythropoietin, SCF increases proliferation and differentiation of myeloid and erythroid progenitor cells and a subset of lymphoid progenitor cells (Broudy). In the mouse, SCF is essential during fetal gonadal development (Mauduit). It is produced by stromal cells in the fetal liver, bone marrow, and thymus, in the central nervous system, in keratinocytes, and in the gut mucosa, and can function as a chemotactic and chemokinetic factor. SCF exists in two biologically active splice forms: a soluble and a transmembrane isoform. Upon binding to its receptor (c-kit tyrosine kinase receptor; CD117), it activates PI3K, JAK/STAT, and MAPK pathways. SCF and signaling from c-kit has also been reported to play an important role in pigmentation, fertility, vasculogenesis, motility of the gut via c-kit-positive interstitial cells of Cajal, and in the migration of neuronal stem and progenitor cells to sites of injury in the brain (Lennartsson and Ronnstrand).

Supplier: Stemcell Technologies

Mouse monoclonal IgG3, kappa isotype control antibody, unconjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1, kappa isotype control antibody, APC-conjugated.

Supplier: Stemcell Technologies

Rat monoclonal IgG2a antibody against mouse CD19, PerCP-Cy5.5-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgM antibody against human, mouse, rat SSEA-1 (CD15), Alexa Fluor® 488-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal antibody against human, rhesus, cynomolgus CD81, unconjugated.

Supplier: Stemcell Technologies

Supplement for the differention to CD14+ monocytes.

Supplier: Stemcell Technologies

Dissociation kit for human stem and progenitor cells.

Supplier: Stemcell Technologies

Rat monoclonal IgG1 antibody against mouse CD25, biotin-conjugated.

Supplier: Stemcell Technologies

A serum-free media kit for the expansion of early-stage human pluripotent stem cell-derived cardiomyocytes.

Supplier: Stemcell Technologies

For detection and measurement of mouse immunoglobulin M.

Supplier: Stemcell Technologies

Animal component-free MSC cryopreservation medium.

Supplier: Stemcell Technologies

Mouse monoclonal antibody against human, monkey CD137 (ILA).