5268 Results for: "ENZO LIFE SCIENCES"
SB202190 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell permeable, potent and selective p38 MAP kinase inhibitor (IC50=30 nM). Inhibits p38α and ß, but not γ and δ isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. A useful tool for dissecting the role of p38 in signaling pathways. Induces apoptosis.
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GW5074 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective cell permeable inhibitor of cRAF1 kinase (IC50 = 9 nM) with 100-fold selectivity over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. A useful tool for assessing the involvement of the Ras/Raf-1/ERK pathway in various signaling pathways. Displays neuroprotective effects in vivo through a MEK-ERK and Akt-independent mechanism.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
24(S)-Hydroxycholesterol ≥98% (by TLC), white solid
Supplier: ENZO LIFE SCIENCES
LXR ligand.
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Acitretin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Retinoic acid receptor ligand.
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Proteasome assay buffer
Supplier: ENZO LIFE SCIENCES
Assay buffer from the 20S Proteasome Assay Kit for Drug Discovery.
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Fluor-de-Lys® Developer I concentrate
Supplier: ENZO LIFE SCIENCES
FLUOR DE LYS® Developer is an essential reagent for signal generation in HDAC or sirtuin assays done with the FLUOR DE LYS® substrate. An appropriate FLUOR DE LYS® family substrate, comprising an acetylated lysine side chain, is first incubated with a sample containing HDAC activity (nuclear or cellular extract, purified enzyme, bead-bound immunocomplex, etc.). Deacetylation of the substrate sensitizes it so that, in a second step, treatment with the FLUOR DE LYS® Developer produces a fluorophore. Typically, an ‘inhibitor stop’ will be included in the 1x Developer dilution (e.g. Trichostatin A) for class I and II HDACs, nicotinamide for sirtuins).
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Nuclear extract from HeLa cells
Supplier: ENZO LIFE SCIENCES
Prepared by high salt extraction of HeLa nuclei (human cervical cancer cell line), this extract is a rich source of HDAC activity, useful for inhibitor screening or immunoprecipitation of HDAC containing complexes. Typically, 0,5 µl or less per well is sufficient for assay with the HDAC FLUOR DE LYS® fluorometric activity assay.
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96-Well assay plates
Supplier: ENZO LIFE SCIENCES
Flat-bottom, half volume, 96-well assay plates.
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Docosa-7Z,10Z,13Z,16Z,19Z-pentaenoic acid ≥98%
Supplier: ENZO LIFE SCIENCES
Polyunsaturated fatty acid.
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Clostridium difficile toxoid A
Supplier: ENZO LIFE SCIENCES
Clostridium difficile toxoid A from Clostridium difficile, strain VPI10463 is a high potency toxin applicable to ELISA, antibody capture, cytotoxicity studies, immunogen and LINE assay.
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Methanandamide ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cannabinoid receptor ligand
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Pertussis Toxin (Bordetella pertussis)
Supplier: ENZO LIFE SCIENCES
Ultra-pure
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PKI (14-22) amide (myristoylated)
Supplier: ENZO LIFE SCIENCES
PKA inhibitor
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[pThr183, pTyr185] MAP kinase (177-189)
Supplier: ENZO LIFE SCIENCES
VHR substrate
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IkappaB Kinase Substrat (Biotin)
Supplier: ENZO LIFE SCIENCES
This peptide sequence, RHDSGLDSMKD, is derived from the area surrounding serine 32 and serine 36 of IκBα, which is phosphorylated by IκB Kinase (IKK).
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Cerulenin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Fatty acid synthase inhibitor
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S-Farnesyl-L-cysteine methyl ester (synthetic) ≥98% (by TLC), colourless oil
Supplier: ENZO LIFE SCIENCES
Multidrug resistance transporter activator.
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(±)-Lisofylline ≥98%
Supplier: ENZO LIFE SCIENCES
Potent inhibitor of phosphatidic acid generation
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Leukotriene D4 ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Prostanoid receptor ligand.
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SEW-2871 ≥98%
Supplier: ENZO LIFE SCIENCES
SEW-2871 is a novel, potent EDG receptor agonist structurally unrelated to sphingosine-1-phosphate and is highly selective for the human S1P1 receptor. It inhibits lymphocyte recirculation in vivo and produces immunosuppression without associated bradycardia which is induced by other less selective S1P agonists. In mice SEW-2871 blocked TNFα induced monocyte adhesion to endothelium.
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1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
PAF receptor ligand.
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Cathepsin S Assay Buffer
Supplier: ENZO LIFE SCIENCES
50mM potassium phosphate buffer, pH 6,5, 50 mM NaCl, 2 mM EDTA, 0,01% Triton X-100®, 0,5 mM DTT.