This antibody recognizes a doublet of 50 kDa and a single band of 42 kDa identified as cyclin E. Cyclin proteins are a family of related proteins, which control the progression of the eukaryotic cell cycle. Overexpression of cyclin E shortens the length of the G1 phase, accelerating progression of S phase. The activity of cyclin E is mediated through its activation of cyclin dependent kinase 2 (cdk2) protein and is modulated by the presence of tumor suppressor proteins such as p16.

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Anti-CK16 Mouse Monoclonal Antibody [clone: LL025]

Supplier: DIAGNOSTIC BIOSYSTEM

This antibody is specific to a 48 kDa protein, which is identified as cytokeratin 16. Cytokeratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region. High concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins.

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Anti-EGFR Mouse Monoclonal Antibody [clone: 111.6]

Supplier: DIAGNOSTIC BIOSYSTEM

This antibody is specific to a 170 kDa protein. EGF-Receptor is a member of the type I family of growth factor receptors. The antibody recognizes an epitope mapping in the extracellular domain of EGFR. Overexpression of EGFR has been reported in tumors of breast, brain, bladder, lung, stomach, head and neck, esophagus, cervix, vulva, ovary and endometrium. EGFR is over expressed in squamous cell carcinoma.

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Anti-P57KIP2 Mouse Monoclonal Antibody [clone: KP39]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-P57KIP2 Mouse Monoclonal Antibody [clone: KP39]

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Anti-ET1 Mouse Monoclonal Antibody [clone: TR.ET.48.5]

Supplier: DIAGNOSTIC BIOSYSTEM

This antibody reacts specifically with human ET-1. The antibody shows 90% cross-reactivity with vasointestinal constrictor, <10% cross-reactivity with ET-2 and ET-3, and no cross-reactivity with sarafotoxin 6c, the C-terminal hexapeptide of ET-1. The endothelins show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells.

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Anti-IgG3 Mouse Monoclonal Antibody [clone: HBME-1]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-IgG3 Mouse Monoclonal Antibody [clone: HBME-1]

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Anti-PGR Mouse Monoclonal Antibody [clone: BV7]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-PGR Mouse Monoclonal Antibody [clone: BV7]

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Anti-GZMB Polyclonal Antibody

Supplier: DIAGNOSTIC BIOSYSTEM

This antibody reacts with a 32 kDa protein. Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTL) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned. Human granzyme B is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. This antibody is useful in the localization of granzyme B containing lytic granules and for the characterization of activated CTL or NK cells.

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Anti-P504S Mouse Monoclonal Antibody [clone: 13H4]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-P504S Mouse Monoclonal Antibody [clone: 13H4]

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Anti-P501S Mouse Monoclonal Antibody [clone: 10000]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-P501S Mouse Monoclonal Antibody [clone: 10000]

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Anti-MGMT Mouse Monoclonal Antibody [clone: MT3.1]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-MGMT Mouse Monoclonal Antibody [clone: MT3.1]

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Anti-BCL10 Mouse Monoclonal Antibody () [clone: 151]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-BCL10 Mouse Monoclonal Antibody [clone: 151]

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Anti-GAL3 Mouse Monoclonal Antibody [clone: 9C4]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-GAL3 Mouse Monoclonal Antibody [clone: 9C4]

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Anti-P53 Rabbit Monoclonal Antibody [clone: SP5]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-P53 Rabbit Monoclonal Antibody [clone: SP5]

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Anti-CGA Rabbit Monoclonal Antibody [clone: SP12]

Supplier: DIAGNOSTIC BIOSYSTEM

This antibody recognizes Chromogranin A. Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.