870 Results for: "DIAGNOSTIC BIOSYSTEM"

Supplier: DIAGNOSTIC BIOSYSTEM

The G168-15 antibody recognizes human and mouse MLH1 (80-85kDa). The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-F13A1 Mouse Monoclonal Antibody [clone: AC-1A1]

Supplier: DIAGNOSTIC BIOSYSTEM

This antibody is specific to a 30 kDa protein known as prohibitin. Prohibitin is an evolutionarily conserved protein located in the inner membrane of mitochondria. Prohibitin shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization and tumor suppression.

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-Cytokeratin 5/14 Mouse Monoclonal Antibody [clone: XM26 + LL002]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-PSMA Mouse Monoclonal Antibody [clone: 3E6]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-Hepatocyte Mouse Monoclonal Antibody [clone: OCH1E5]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-CDX2 Mouse Monoclonal Antibody [clone: AMT28]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-CD7 Mouse Monoclonal Antibody [clone: CBC.37]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-HSVII Rabbit Polyclonal Antibody

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-MDM2 Rabbit Polyclonal Antibody

Supplier: DIAGNOSTIC BIOSYSTEM

Recognizes a protein named estrogen receptor (ER) α. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland.

Supplier: DIAGNOSTIC BIOSYSTEM

This antibody reacts with a 70 kDa protein. COX-2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters and cytokines that induce its expression. COX-2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX-1 levels remained unchanged.

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-CASP9 Rabbit Polyclonal Antibody

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-P16Ink4 Mouse Monoclonal Antibody [clone: DCS-50]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-APAF 1 Rabbit Polyclonal Antibody

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-APP Rabbit Monoclonal Antibody

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-SYP Rabbit Monoclonal Antibody [clone: SP11]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-c-erbB2 Mouse Monoclonal Antibody [clone: SP3]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-CALB2 Rabbit Polyclonal Antibody

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-ACTH Rabbit Polyclonal Antibody

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-ESR Rabbit Monoclonal Antibody [clone: SP1]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-AFP Rabbit Polyclonal Antibody

Supplier: DIAGNOSTIC BIOSYSTEM

This antibody recognizes p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein. p53 senses DNA damage and possibly facilitates repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-alpha-Actinin (Sarcomeric) Mouse Monoclonal Antibody [clone: EA-53]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-Retinoblastoma Mouse Monoclonal Antibody [clone: 1F8]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-Transforming Groth Factor A Mouse Monoclonal Antibody [clone: MF9+TG86]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-Mast Cell Tryptase Mouse Monoclonal Antibody [clone: AA1]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-NRG1 Mouse Monoclonal Antibody [clone: 7D5]

Supplier: DIAGNOSTIC BIOSYSTEM

Anti-Ku70 Mouse Monoclonal Antibody [clone: S5C11]

Supplier: DIAGNOSTIC BIOSYSTEM

This antibody reacts with cytokeratins of acidic as well as basic subfamilies, i.e. 1, 2, 3, 4, 5, 6, 7, 8, 10, 12, 13, 14, 15, 16, 17, 18 and 19. It reacts with keratinized and corneal epidermis, stratified epithelia, hyperproliferative keratinocytes and simple epithelia. This antibody is a broad spectrum anti-pan cytokeratin antibody, which differentiates epithelial from non-epithelial tumors.