"Benzilic+acid&amp"

Supplier: Bioss

FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. EPB41L5 (erythrocyte membrane protein band 4.1 like 5), also known as BE37 or YMO1, is a 733 amino acid cytoplasmic protein that contains one FERM domain, which it uses to bind CRB1 (crumbs homolog 1). EPB41L5 is a homolog of zebrafish 'mosaic eyes' (moe), and is widely expressed but found at highest levels in ovary, kidney and brain, and is known to colocalize with _-catenin. EPB41L5 may participate in tight junction positioning during the establishment of epithelial cell polarity, and exists as four alternatively spliced isoforms that are encoded by a gene located on human chromosome 2q14.2.

Supplier: Bioss

RILPL2 is a 211 amino acid protein that belongs to the RILPL family. RILPL2 does not regulate lysosomal morphology or distribution. RILPL2 shares 32% and 18% amino acid identity with RILPL1 and RILP, respectively. RILPL2 as a novel interacting partner for the actin-based molecular motor MyoVa, and has a novel role for RILPL2 in controlling neuronal morphogenesis. It has been suggested that there is also a novel role for RILPL2 in the regulation of cellular shape and dendritic-spine morphogenesis, probably via the Rac1-Pak pathway. PCR analysis of human tissues detects highest RILPL2 expression in lung, followed by placenta. Lower expression is detected in liver, kidney, pancreas, heart and brain, but no expression is detected in skeletal muscle. The RILPL2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 12q24.31.

Supplier: Bioss

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

Supplier: TCI

Isoamyl salicylate (contains 2-Methylbutyl Salicylate)

Supplier: TCI

3,4-Difluorophenyl isocyanate ≥98.0% (by GC)

Supplier: TCI

Methyl-2-chloro-4-nitrobenzoate ≥99.0% (by GC)

Supplier: VWR Chemicals

RbNO₃ in HNO₃ 2 to 5%.

Supplier: VWR Chemicals

RbNO₃ in HNO₃ 2 to 5%.

Supplier: Apollo Scientific

Usage: Organic building block/ reagent.

Supplier: Apollo Scientific

Fmoc-L-homopropargylglycine

Supplier: Apollo Scientific

Odevixibat

Supplier: Thermo Fisher Scientific

L(+)-Histidine 98%

Supplier: TCI

Methyl aziridine-2-carboxylate ≥97.0% (by GC, titration analysis) stabilised

Supplier: Apollo Scientific

L-Thr(Me)-OH

Supplier: VWR Chemicals

Ammonium sulphate ≥99%, GPR RECTAPUR®

Supplier: Apollo Scientific

Usage: Inorganic salt or catalyst.