253828 Results for: "Abcam"

Supplier: Abcam

PI-103 1 * 1 mg

Supplier: Abcam

Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. HSP47 is a molecule expressed constitutively in cells that s ynthesizes collagen. HSP47 is a procollagen-specific molecular chaperon that resides in the endoplasmic reti 1 * 100 µG

Supplier: Abcam

TEMSIROLIMUS (CCI-779, TORISEL) 1 * 25 mg

Supplier: Abcam

Cell cycle progression is subject to arrest at the mitotic spindle assembly checkpoint in response to incorrect spindle fiber assemb ly. MAD1 and MAD2 (for mitotic arrest-deficient 1 and 2) are components of the mitotic spindle checkpoint. I 1 * 100 µl

Supplier: Abcam

Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting, and is essenti al for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes 1 * 50 µG

Supplier: Abcam

ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase 1 * 100 µl

Supplier: Abcam

JNK/SAPK-inhibitory kinase (JIK) is a serine/threonine kinase that belongs to the STE20 kinase family. The kinase domain of JIK is s imilar to the GCK-like subfamily of STE20 kinases, while its non-catalytic domain is similar to a Caenorhabd 1 * 100 µl

Supplier: Abcam

Mitochondrial Trifunctional Protein (TFP) is a multienzyme complex of the beta-oxidation cycle. TFP deficiency is a clinically heter ogeneous disorder with phenotypes of different severity. The spectrum of diseases range from severe neonatal 1 * 100 µG

Supplier: Abcam

Translocase of the mitochondria Outer Membrane (TOM) is essential for protein import into mitochondria. TOM40 is synthesized in the cytosol and contains information for its mitochondrial targeting and assembly. 1 * 100 µG

Supplier: Abcam

Visfatin is a cytokine highly expressed in visceral fat and blood. This protein has also been reported to be a cytokine (PBEF) that promotes B cell maturation and inhibits neutrophil apoptosis. 1 * 100 µG

Supplier: Abcam

Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways 1 * 50 µG

Supplier: Abcam

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin 1 * 50 µG

Supplier: Abcam

Polycomb group (PcG) genes encode chromatin proteins that are involved in the maintenance of cellular memory throμgh epigenetic chro matin modifications. Bmi-1 has been identified among the PcG genes as a potent oncogene that plays an import 1 * 100 µG

Supplier: Abcam

Telomerase is an RNA-dependant DNA polymerase that catalyzes the addition of telemoric repeat, TTAGGG to chromosome ends. Telomerase is composed of an internal telomerase RNA template (TERC) and the enzyme, telomerase reverse transcriptase 1 * 100 µG

Supplier: Abcam

Sphingosine Kinase (SphK) is a conserved lipid kinase that catalyzes the phosphorylation of sphingolipid sphingosine to sphingosine- 1-phosphate (SIP). SIP receptors coupled to cell surface G protein to regulate cell growth, 1 * 100 µG

Supplier: Abcam

Serpin A6 is a secreted glycoprotein that belongs to the serpin family of protease inhibitors. null

Supplier: Abcam

Prohibitin is an evolutionarily conserved protein that has anti-proliferative activity. Prohibitin is a 30 kDa, post-synthetically modified protein found in the inner membrane of mitochondria and on the plasma membrane of B cells. 1 * 100 µG

Supplier: Abcam

ALDH2 (Aldehyde dehydrogenase 2 family) belongs to the aldehyde dehydrogenase family which catalyze the chemical transformation from acetaldehyde to acetic acid and is the second enzyme of the major oxidative pathway of alcohol metabolism. 1 * 100 µl

Supplier: Abcam

AS160 is a 160 kDa Akt serine/threonine kinase substrate that plays a critical role in regulating insulin-stimulated exocytosis of g lucose transporter GLUT4. Increased in insulin treatment stimulate phophorylation of AS160 1 * 100 µG

Supplier: Abcam

Human sirtuins function as intracellular regulatory proteins. Sirtuin 2 is a member of the class III histone deacetylases (HDACs) an d has been implicated in many cellular processes that include histone deacetylation, gene silencing 1 * 100 µG

Supplier: Abcam

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This prote in interacts with PPARgamma, which permits the interaction of this protein with multiple transcription facto 1 * 100 µG

Supplier: Abcam

S-tag is an epitope tag composed of a 15 residue peptide derived from pancreatic ribonuclease A 1 * 100 µG

Supplier: Abcam

FGF-7, also known as Keratinocyte Growth Factor (KGF), is a potent mitogen for keratinocytes and epithelial cells. The antibody reco gnizes ~19 kDa of human FGF-7/KGF protein containing 163 amino acid residues. 1 * 100 µG

Supplier: Abcam

ANNEXIN V-BIOTIN APOPTOSIS KIT 1 * 400 Assays

Supplier: Abcam

Fas/Apo-1/CD95 is a cell surface type-I membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. Fas is a memb er of the TNFR family that includes TNFR1, TNFR2, CD27, CD30, and CD40. Binding of Fas-ligand (FasL) to Fas 1 * 100 µG

Supplier: Abcam

Acyl-CoA dehydrogenase, very long chain (ACADVL) is a member of the acyl-CoA dehydrogenases family. ACADVL is an inner mitochondrial membrane protein that catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. 1 * 100 µG

Supplier: Abcam

mCherry is an engineered derivative of one of a family of proteins originally isolated from Cnidarians (jelly fish, sea anemones and corals). mCherry is the second generation monomeric red fluorescent protein that have improved brightness 1 * 100 µG

Supplier: Abcam

Nitrotyrosine is a product of tyrosine nitration mediated by reactive nitrogen species such as peroxynitrite anion and nitrogen diox ide. It is a marker for inflammation and nitric oxide (NO) production. 1 * 50 µG

Supplier: Abcam

EGF-D is most closely related to VEGF-C by virtue of the presence of N- and C-terminal extensions that are not found in other VEGF f amily members. In adult human tissues, VEGF-D mRNA is most abundant in heart, lung, skeletal muscle, colon, 1 * 100 µG

Supplier: Abcam

BAFF (for B cell Activating Factor) is a novel member in the TNF family. BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified 1 * 100 µG