162358 Results for: "3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione"
3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione ≥98%
Supplier: ENZO LIFE SCIENCES
PKC inhibitor
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3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione ≥97.0% (by HPLC)
Supplier: TCI
3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione ≥97.0% (by HPLC)
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1-Methyl-3,4-bis(3-indolyl)maleimide ≥98%
Supplier: ENZO LIFE SCIENCES
Negative control for the protein kinase C (PKC)-inhibitory activity.
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Bisindolylmaleimide I
Supplier: Apollo Scientific
Inhibitor of protein kinase C.
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Gö 6983 ≥99%
Supplier: Apollo Scientific
Gö 6983 is a potent, cell-permeable, ATP-competitive inhibitor of protein kinase C (PKC).
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Bisindolylmaleimide I ≥97.0% (by HPLC)
Supplier: TCI
Bisindolylmaleimide I ≥97.0% (by HPLC)
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Gö 6983 ≥95% (by HPLC)
Supplier: ENZO LIFE SCIENCES
PKC inhibitor. Has been shown to selectively inhibit several PKC isoenzymes (IC50 = 7nM for PKCα and PKCβ; 6nM for PKCγ; 10nM for PKCδ; 60nM for PKCζ). The compound does not effectively inhibit PKCµ (IC50=20 µM) and therefore can be used to differentiate PKCµ from other isoforms.
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Bisindoylmaleimide X hydrochloride ≥98%
Supplier: ENZO LIFE SCIENCES
PKC inhibitor
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Bisindolylmaleimide I ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
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SB216763 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model.
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IM-54 ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Cell permeable inhibitor of necrosis. Selectively blocks oxidative stress-induced necrotic cell death (~3 µm IM-54 prevented ~50% cell death in HL60 cells exposed to 100 µm H2O2). Does not protect against etoposide-induced apoptosis or display antioxidant properties. Does not affect S6K1 and PKC kinase activities at concentrations of 50 µm.
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3,4-Dibromo-1H-pyrrole-2,5-dione ≥98.0% (by HPLC, titration analysis)
Supplier: TCI
3,4-Dibromo-1H-pyrrole-2,5-dione ≥98.0% (by HPLC, titration analysis)
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3,4-Dibromo-1H-pyrrole-2,5-dione 98%
Supplier: Apollo Scientific
3,4-Dibromo-1H-pyrrole-2,5-dione 98%
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3,4-Dibromo-1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione
Supplier: Apollo Scientific
3,4-Dibromo-1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione
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1-(1-Methyl-1H-indazol-3-yl)-1H-pyrrole-2,5-dione
Supplier: Apollo Scientific
1-(1-Methyl-1H-indazol-3-yl)-1H-pyrrole-2,5-dione
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1-(1-Naphthyl)-1H-pyrrole-2,5-dione
Supplier: Apollo Scientific
1-(1-Naphthyl)-1H-pyrrole-2,5-dione
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3,6-Di(2-thienyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione ≥95.0% (by HPLC, total nitrogen)
Supplier: TCI
3,6-Di(2-thienyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione ≥95.0% (by HPLC, total nitrogen)
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2,5-Bis(2-ethylhexyl)-3,6-di(2-thienyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione ≥98.0% (by HPLC)
Supplier: TCI
2,5-Bis(2-ethylhexyl)-3,6-di(2-thienyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione ≥98.0% (by HPLC)
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Bisindolylmaleimide I
Supplier: Thermo Fisher Scientific
Very potent and selective inhibitor of protein kinase C.
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FIM-1, Sigma-Aldrich®
Supplier: SIGMA ALDRICH MICROSCOPY
A fluorescent conjugate of bisindolylmaleimide that specifically binds phosphokinase C at the active site. Can monitor enzyme activation and translocation. This reagent is not membrane permeable. The diacetate form (Sigma No. F9801) is membrane permeable.
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Fluorescein-5-maleimide ≥90% (by HPLC), Ultrapure
Supplier: ENZO LIFE SCIENCES
Thiol dye
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7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM), Sigma-Aldrich®
Supplier: SIGMA ALDRICH MICROSCOPY
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin has been used: as a nontoxic substitute for conjugation with antibody(93) to aid fluorescent detection of Coenzyme A (CoA-SH) in human N-myristoyltransferases assay (94)
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N-(1-Pyrenyl)maleimide ≥97.0% (by HPLC)
Supplier: TCI
N-(1-Pyrenyl)maleimide ≥97.0% (by HPLC)
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N-Propargylmaleimide ≥98.0% (by HPLC, total nitrogen)
Supplier: TCI
N-Propargylmaleimide ≥98.0% (by HPLC, total nitrogen)
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Fluorescein-5-maleimide ≥97.0% (by HPLC) (contains 2% N,N-Dimethylformamide at maximum)
Supplier: TCI
Fluorescein-5-maleimide ≥97.0% (by HPLC) (contains 2% N,N-Dimethylformamide at maximum)
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U-73122 ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of PLC activation
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BMH (1,6-Bis(maleimido)hexane) 97%
Supplier: Thermo Fisher Scientific
BMH (1,6-Bis(maleimido)hexane) 97%