Purospher® RP-18 is designed for the separation of problematic basic compounds with simple neutral eluents. In addition Purospher® RP-18 allows the separation of hydrophilic compounds with aqueous mobile phase. Purospher® RP-18 is based upon a high purity, metal-free silica. The multi-step chemical modification and deactivation of the surface, and the polar endcapping, enables a peak-tailing-free elution of basic and chelating compounds. Purospher® RP-18 is not suitable for the separation of acidic compounds. The good chemical stability of Purospher® RP-18 enables the use of mobile phase conditions at pH 8 for a long period of time.

Purospher® RP-18e is a versatile, high purity HPLC column producing excellent peak shapes, designed for both the separation of basic compounds with simple neutral eluents, and for the elution of strongly acidic compounds. Excellent separations in a shorter period of time with very good peak symmetry saves time and money. The excellent balance of Purospher® RP-18e, in the sum of its chromatographic properties, is the key to better separations of complex samples with simpler, neutral eluents. The good chemical stability of Purospher® RP-18e enables the use of mobile phase conditions at pH 8 for a long period of time.

These LiChroCART® cartridges require part number 1.51486.0001 manu-CART® cartridge column holder, which can be used to hold one cartridge column with or without a 4×4 mm guard column.