GM-CSF is a hematopoietic growth factor with the ability to form colonies of granulocytes and macrophages. Enhances the number of circulating white blood cells and function of neutrophils and monocytes. Regulates multiple functions via transcription factors in the differentiated cells, including cell survival, proliferation, and maturation. Generates in vitro murine and human DC populations from bone marrow precursors and blood monocytes, respectively.

• High Quality
• Low Endotoxin
• Lot-to-lot Consistency
• Animal Free
• Manufactured following GMP guidelines

Human and mouse GM-CSF do not show cross-reactivity. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.

The CTGrade GMP products are manufactured in a facility that does not use or process beta-lactam containing materials. No animal- or human-derived materials were used during manufacturing or as ingredients.

Shelf life: Unopened vials are stable for 36 months from the date of manufacture as indicated on the label. Reconstituted material should be apportioned in working volumes and stored at or below −20°C in manual defrost freezer. For short term storage reconstituted material is stable for 4 to 6 weeks when stored at 2 to 8 °C. Stability can be increased by adding at least 0.1% carrier protein.

Host cell Protein: ≤30 ng/ml
Host cell DNA: ≤0,01 ng/ml
Sterility testing: No growth
Mycoplasma: Negative