Animal component-free collagenase for the digestion of native collagen fibrils.

• Obtain cleaner cultures with an animal component-free solution

Use Collagenase C, Animal Component-Free (ACF) to digest native collagen fibrils in connective tissues and prevent the introduction of animal-derived pathogens. This enzymatic preparation is sourced from Clostridium histolyticum and is obtained from cultures free of animal-derived materials. Collagenase preparations contain the activity of several proteases including: collagenase, caseinase, clostripain, and trypsin (Kessler and Yaron). Similar to Collagenase Type IV, Collagenase C, ACF contains low levels of tryptic activity, limiting damage to membrane proteins and receptors.