Use of tetraethylammonium (TEA) and Tris loading for blocking TRPM7 channels in intact cells.: This study highlights the application of TRIS Hydrochloride in blocking TRPM7 channels, which is significant for cell signaling and ion channel regulation in pharmacological research (Holderby & Kozak, 2024).

• Assay: ≥99%
• pKa (25 °C) 8,1

Investigating the influence of solvent type and pH on protein adsorption onto silica surface by evanescent-wave cavity ring-down spectroscopy.: This study uses TRIS Hydrochloride to explore protein-silica interactions, providing insights into surface chemistry and biomolecular adsorption processes (Alnaanah & Mendes, 2024).

The pH values of all buffers are temperature and concentration dependent. For Tris buffers, pH increases about 0,03 unit per °C decrease in temperature, and decreases 0,03 to 0,05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.