Anti-APPBP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
BOSSBS-12503R-A680
: Bioss
- Antibody type:Primary
- Antigen name:APPBP1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat,Mouse
- Western blot:Yes
- Epitope:401-500/534
- Form:Liquid
- Gene ID:8883
- Antigen synonyms:NAE1|Amyloid beta precursor protein-binding protein 1, 59 kDa|APPBP1|Proto-oncogene protein 1|A-116A10.1|NEDD8-activating enzyme E1 regulatory subunit|ula-1|APP-BP1|HPP1|Amyloid protein-binding protein 1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:60 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human APPBP1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
Type: Primary
Antigen: APPBP1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 401-500/534
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat