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Anti-CD80 Armenian Hamster Antibody [clone: 16-10A1]
Anti-CD80 Armenian Hamster Antibody [clone: 16-10A1]
Catalog # 40-0801-U100
Supplier:  Tonbo Biosciences
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Anti-CD80 Armenian Hamster Antibody [clone: 16-10A1]
Catalog # 40-0801-U100
Supplier:  Tonbo Biosciences

Specifications

  • Antigen name:
    CD80 molecule
  • Antigen symbol:
    CD80
  • Clone:
    16-10A1
  • Flow cytometry:
    Yes
  • Host:
    Armenian hamster
  • ImmunoChemistry:
    Yes
  • ImmunoPrecipitation:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Mouse
  • Gene ID:
    12519
  • Antigen synonyms:
    TSA1|B71|Ly-53|MIC17|Cluster of Differentiation 80|Cd28l|Ly53
  • Storage temperature:
    Store undiluted at 2-8 °C, protect from light, do not freeze.
  • Tested applications:
    Functional Assay, Immunofluorescence Microscopy
  • Pk:
    100 µG

Specifications

About this item

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Type:
Antigen: CD80
Clonality:
Clone: 16-10A1
Conjugation:
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: