About this item
Neurotrophin-4 (NT-4) is an important member of the nerve growth factor (NGF) family of proteins. Neurotrophins undergo paracrine and autocrine signaling to control neuronal survival, neuronal differentiation, and dendrite outgrowth. NT-4 is expressed ubiquitously and signals through the TrkB receptor tryrosine kinase.
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Galectin-1 belongs to the lectin family of carbohydrate binding proteins and binds glycans as both a monomer and a homodimer. Galectin-1 is produced in peripheral lymphoid organs and inflammatory sites. Galectin-1 plays important roles in acute and chronic inflammatory processes, cell growth, cell proliferation, and induces apoptosis of activated T cells. Galectin-1 also modulates cytokine secretion and inhibits pro-inflammatory cytokine production.
Specifications
- Conjugation:Unconjugated
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:−20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤1
- Biological activity:Bioactivity: No biological activity data is available at this time
- Gene ID:P09382
- Reconstitution instructions:Sterile water at 0,1 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:Y
- Protein synonyms:S-LAC lectin-I|L-14|Beta-galactoside-binding lectin L-14-I|galaptin
- UniProtKB:P09382
- Protein/peptide name:Galectin-1
- Purity:≥95%
- Molecular weight:14,7 kDa
- Sequence:MACGLVASNL NLKPGECLRV RGEVAPDAKS FVLNLGKDSN NLCLHFNPRF NAHGDANTIV CNSKDGGAWG TEQREAVFPF QPGSVAEVCI TFDQANLTVK LPDGYEFKFP NRLNLEAINY MAADGDFKIK CVAFD
- Endotoxin level:Low
- Formulation:10 mM sodium phosphate, pH 7,5
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT