Human Recombinant GDNF (from E. coli)
Supplier: Shenandoah Biotechnology
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About this item
Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.
- High quality
- Low endotoxin
- Affordable
Caution: For research use only.
Specifications
- Conjugation:Unconjugated
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:–20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0,1
- Biological activity:Bioactivity Assay: C₆ proliferation, ED₅₀ ≤3 µg/ml, Bioactivity ≥3,3×10² units/mg
- Gene ID:P39905
- Reconstitution instructions:Sterile water at 0,1 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:N
- Protein synonyms:ATF-1
- Protein/peptide name:GDNF
- Purity:≥95%
- Molecular weight:15,2/30,4 kDa
- Sequence:MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI
- Endotoxin level:Low
- Formulation:10 mM Sodium citrate, 100 mM Sodium chloride, pH 4,0
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT
- Tested applications:Bioassay