Mouse Recombinant IL-4 (from E. coli)
Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.
- High quality
- Low endotoxin
- Affordable
: For research use only.
- Conjugation:Unconjugated
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Mouse
- Storage conditions:–20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0,1
- Biological activity:Bioactivity Assay: HT-2 proliferation, ED₅₀ ≤20 ng/ml, Bioactivity ≥5,0×10⁴ units/mg
- Gene ID:P07750
- Reconstitution instructions:Sterile water at 0,1 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:N
- Protein synonyms:BCGF|B cell Stimulating Factor|BCDF|BSF-1
- Protein/peptide name:IL-4
- Purity:≥95%
- Molecular weight:13,7 kDa
- Sequence:MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
- Endotoxin level:Low
- Formulation:0,1% Trifluoroacetic acid (TFA)
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT
- Tested applications:Bioassay