Spesifikasjoner

Pk:
50 µG
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Tag sequence:
N-6 His tag
Storage conditions:
Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Protein synonyms:
Rapamycin-selective 25 kDa immunophilin|FKBP-25|25 kDa FKBP|FKBP3|Peptidyl-prolyl cis-trans isomerase FKBP3|Immunophilin FKBP25|FKBP25|PPIase FKBP3|Rotamase|25 kDa FK506-binding protein|FK506-binding protein 3|FKBP-3
Protein/peptide name:
FKBP25
Purity:
> 95% as determined by reducing SDS-PAGE
Molecular weight:
27.3 kD
Sequence:
Met1-Asp224
Formulation:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl，1mM DTT,10% glycerol . Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested applications:
Bioassay

Spesifikasjoner

Om dette produktet

FKBP3 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Fusion-Tag: N-6 His tag

This recombinant protein can be used for biological assays. For research use only.