Order Entry
Norway
ContactUsLinkComponent
 
Human recombinant interleukin 6 (from HEK293 cells)
  PRSI96-446
 :  
undefined
Human recombinant interleukin 6 (from HEK293 cells)
  PRSI96-446
 :  

 

  • Pk:
    20 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    HEK293 cells
  • Species:
    Human
  • Biological activity:
    The bio-activity was determined by dose-dependent stimulation of the proliferation of mouse B9 hybridoma cells. The ED50 < 0. 05 ng/mL, corresponding to a specific activity of >2X107 Unit/mg. Measured by its binding ability in a functional ELISA. Immobilized Human IL-6 /Interleukin-6 Protein,HEK293 expressed at 5μg/mL (100 μL/well),can bind Recombinant Human IL6R /CD126 Protein. The EC50 is typically 0. 05-0. 4μg/mL.
  • Protein synonyms:
    Interleukin-6|HSF|HGF|IFNB2|IL6|BSF2
  • Protein/peptide name:
    Interleukin 6
  • Purity:
    >98% as determined by SDS-PAGE.
  • Molecular weight:
    20.8 kDa
  • Formulation:
    Lyophilized, PBS, pH7.4
  • Tested applications:
    Western Blot

 

 

Interleukin 6 (IL-6) is also known as HGF, BSF2,HSF, IFNB2 and IL-6, originally identified as a B cell differentiation factor, is a multifunctional cytokine that regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions.It is secreted by T cells, macrophages , monocytes, fibroblasts,endothelial cells,et.al. to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. IL-6 is relevant to many disease processes such as diabetes,atherosclerosis, depression,Alzheimer's Disease,systemic,lupus erythematosus,prostate cancer and rheumatoid arthritis. Advanced/metastatic cancer patients have higher levels of IL-6 in their blood.Hence there is an interest in developing anti-IL-6 agents as therapy against many of these diseases.