- Antigen name:WD Repeat Domain 35
- Antigen symbol:WDR35
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Antigen synonyms:WD repeat-containing protein 35|IFT121|KIAA1336|CED2|SRTD7|Intraflagellar transport protein 121 homolog|WDR35|IFTA1
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:WDR35 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human WDR35.
- Tested applications:E, IHC
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
WDR35 Antibody: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.
Type:
Antigen: WDR35
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human