Spesifikasjoner
- Antibody type:Primary
- Antigen name:Y box binding Protein 1
- Antigen symbol:YB1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 647
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Cross adsorption:No
- Form:liquid
- Gene ID:4904
- Antigen synonyms:CCAAT-binding transcription factor I subunit A|EFI-A|YB1|DBPB|CBF-A|Y-box-binding protein 1|NSEP-1|nuclease-sensitive element-binding protein 1|CSDA2|Y box-binding protein I|DNA-binding protein B|major histocompatibility complex|NSEP1|MDR-NF1|class II|BP-8|MGC110976|enhancer factor I subunit A|MGC117250|CSDB|nuclease sensitive element binding protein 1|YB-1|MGC104858|Y-box transcription factor
- Modification:phospho-Ser102
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:80-120/324
- Purification:Purified by Protein A
- Pk:100 µl
Spesifikasjoner
Om dette produktet
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: YB1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat